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Substrate-specific effects of natural genetic variation on proteasome activity
Protein degradation is an essential biological process that regulates protein abundance and removes misfolded and damaged proteins from cells. In eukaryotes, most protein degradation occurs through the stepwise actions of two functionally distinct entities, the ubiquitin system and the proteasome. U...
Autores principales: | Collins, Mahlon A., Avery, Randi, Albert, Frank W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174532/ https://www.ncbi.nlm.nih.gov/pubmed/37126494 http://dx.doi.org/10.1371/journal.pgen.1010734 |
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