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Psychological burden of achalasia: Patients’ screening rates of depression and anxiety and sex differences

OBJECTIVE: Achalasia is associated with reduced quality of life in affected patients but research regarding the psychological burden of achalasia in terms of depression and anxiety is scarce. The current study therefore aims to investigate rates of depression and anxiety in patients with achalasia i...

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Autores principales: Hanschmidt, Franz, Treml, Julia, Deller, Julia, Kreuser, Nicole, Gockel, Ines, Kersting, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174570/
https://www.ncbi.nlm.nih.gov/pubmed/37167311
http://dx.doi.org/10.1371/journal.pone.0285684
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author Hanschmidt, Franz
Treml, Julia
Deller, Julia
Kreuser, Nicole
Gockel, Ines
Kersting, Anette
author_facet Hanschmidt, Franz
Treml, Julia
Deller, Julia
Kreuser, Nicole
Gockel, Ines
Kersting, Anette
author_sort Hanschmidt, Franz
collection PubMed
description OBJECTIVE: Achalasia is associated with reduced quality of life in affected patients but research regarding the psychological burden of achalasia in terms of depression and anxiety is scarce. The current study therefore aims to investigate rates of depression and anxiety in patients with achalasia in relation to prevalence rates in the general population and to examine the extent to which achalasia-related characteristics (time since diagnosis, symptom load, achalasia-related quality of life, treatment history) predict symptoms of depression and anxiety. METHODS: Using validated screening instruments, rates of depression and anxiety were assessed in a cross-sectional survey of a sample of 993 patients with achalasia and compared to population controls stratified by age and sex. Associations between depression and anxiety and achalasia-related factors were explored using linear regression. RESULTS: Compared to population controls, screening rates of female patients with achalasia were between 3.04 (p = .004) and 7.87 (p < .001) times higher for depression and 3.10 (p < .001) times higher for anxiety, respectively. No significant differences were found for male patients with achalasia. Both achalasia-related quality of life and symptom load were independently related to impaired mental health. CONCLUSION: Women appear to be specifically affected by the psychological burden of achalasia, pointing to sex-specific or gendered experiences of the disease. In addition to symptom reduction, psychological support may prove beneficial for improving the well-being of patients with achalasia.
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spelling pubmed-101745702023-05-12 Psychological burden of achalasia: Patients’ screening rates of depression and anxiety and sex differences Hanschmidt, Franz Treml, Julia Deller, Julia Kreuser, Nicole Gockel, Ines Kersting, Anette PLoS One Research Article OBJECTIVE: Achalasia is associated with reduced quality of life in affected patients but research regarding the psychological burden of achalasia in terms of depression and anxiety is scarce. The current study therefore aims to investigate rates of depression and anxiety in patients with achalasia in relation to prevalence rates in the general population and to examine the extent to which achalasia-related characteristics (time since diagnosis, symptom load, achalasia-related quality of life, treatment history) predict symptoms of depression and anxiety. METHODS: Using validated screening instruments, rates of depression and anxiety were assessed in a cross-sectional survey of a sample of 993 patients with achalasia and compared to population controls stratified by age and sex. Associations between depression and anxiety and achalasia-related factors were explored using linear regression. RESULTS: Compared to population controls, screening rates of female patients with achalasia were between 3.04 (p = .004) and 7.87 (p < .001) times higher for depression and 3.10 (p < .001) times higher for anxiety, respectively. No significant differences were found for male patients with achalasia. Both achalasia-related quality of life and symptom load were independently related to impaired mental health. CONCLUSION: Women appear to be specifically affected by the psychological burden of achalasia, pointing to sex-specific or gendered experiences of the disease. In addition to symptom reduction, psychological support may prove beneficial for improving the well-being of patients with achalasia. Public Library of Science 2023-05-11 /pmc/articles/PMC10174570/ /pubmed/37167311 http://dx.doi.org/10.1371/journal.pone.0285684 Text en © 2023 Hanschmidt et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Hanschmidt, Franz
Treml, Julia
Deller, Julia
Kreuser, Nicole
Gockel, Ines
Kersting, Anette
Psychological burden of achalasia: Patients’ screening rates of depression and anxiety and sex differences
title Psychological burden of achalasia: Patients’ screening rates of depression and anxiety and sex differences
title_full Psychological burden of achalasia: Patients’ screening rates of depression and anxiety and sex differences
title_fullStr Psychological burden of achalasia: Patients’ screening rates of depression and anxiety and sex differences
title_full_unstemmed Psychological burden of achalasia: Patients’ screening rates of depression and anxiety and sex differences
title_short Psychological burden of achalasia: Patients’ screening rates of depression and anxiety and sex differences
title_sort psychological burden of achalasia: patients’ screening rates of depression and anxiety and sex differences
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174570/
https://www.ncbi.nlm.nih.gov/pubmed/37167311
http://dx.doi.org/10.1371/journal.pone.0285684
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