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Expression of RNA polymerase I catalytic core is influenced by RPA12

RNA Polymerase I (Pol I) has recently been recognized as a cancer therapeutic target. The activity of this enzyme is essential for ribosome biogenesis and is universally activated in cancers. The enzymatic activity of this multi-subunit complex resides in its catalytic core composed of RPA194, RPA13...

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Detalles Bibliográficos
Autores principales: Ford, Brittany L., Wei, Ting, Liu, Hester, Scull, Catherine E., Najmi, Saman M., Pitts, Stephanie, Fan, Wenjun, Schneider, David A., Laiho, Marikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174586/
https://www.ncbi.nlm.nih.gov/pubmed/37167337
http://dx.doi.org/10.1371/journal.pone.0285660