Age-related differences in prefrontal glutamate are associated with increased working memory decay that gives the appearance of learning deficits

The ability to use past experience to effectively guide decision-making declines in older adulthood. Such declines have been theorized to emerge from either impairments of striatal reinforcement learning systems (RL) or impairments of recurrent networks in prefrontal and parietal cortex that support...

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Detalles Bibliográficos
Autores principales: Rmus, Milena, He, Mingjian, Baribault, Beth, Walsh, Edward G, Festa, Elena K, Collins, Anne GE, Nassar, Matthew R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174689/
https://www.ncbi.nlm.nih.gov/pubmed/37070807
http://dx.doi.org/10.7554/eLife.85243

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