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Neither random nor censored: estimating intensity-dependent probabilities for missing values in label-free proteomics

MOTIVATION: Mass spectrometry proteomics is a powerful tool in biomedical research but its usefulness is limited by the frequent occurrence of missing values in peptides that cannot be reliably quantified (detected) for particular samples. Many analysis strategies have been proposed for missing valu...

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Detalles Bibliográficos
Autores principales: Li, Mengbo, Smyth, Gordon K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174703/
https://www.ncbi.nlm.nih.gov/pubmed/37067487
http://dx.doi.org/10.1093/bioinformatics/btad200