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Mucoepidermoid carcinoma cured by a combination of high‐frequency snare and photodynamic therapy: A case report

Mucoepidermoid carcinoma (MEC) is a rare salivary gland tumor, accounting for 0.2% of all lung tumors. The standard treatment for MEC of the primary bronchus is surgery, although intraluminal bronchoscopic treatment has recently become an option. A 68‐year‐old man presented with an asymptomatic bron...

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Autores principales: Tamura, Kentaro, Uchimura, Keigo, Furuse, Hideaki, Imabayashi, Tatsuya, Matsumoto, Yuji, Tsuchida, Takaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175029/
https://www.ncbi.nlm.nih.gov/pubmed/36929314
http://dx.doi.org/10.1111/1759-7714.14861
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author Tamura, Kentaro
Uchimura, Keigo
Furuse, Hideaki
Imabayashi, Tatsuya
Matsumoto, Yuji
Tsuchida, Takaaki
author_facet Tamura, Kentaro
Uchimura, Keigo
Furuse, Hideaki
Imabayashi, Tatsuya
Matsumoto, Yuji
Tsuchida, Takaaki
author_sort Tamura, Kentaro
collection PubMed
description Mucoepidermoid carcinoma (MEC) is a rare salivary gland tumor, accounting for 0.2% of all lung tumors. The standard treatment for MEC of the primary bronchus is surgery, although intraluminal bronchoscopic treatment has recently become an option. A 68‐year‐old man presented with an asymptomatic bronchial tumor in the right intermediate bronchus. The tumor was resected using a high‐frequency snare (HFS) during bronchoscopy, and the specimen was pathologically diagnosed as low‐grade MEC. A residual lesion was detected in the resected area by autofluorescence imaging. The tumor appeared to be localized within the subepithelial layer without metastases, and photodynamic therapy (PDT) was performed as a local treatment. The patient had no recurrence for 18 months. PDT is effective and safe for patients with centrally located early‐stage lung cancer, but there are few reports of its use for rare tumors, such as MEC. In this case, PDT allowed for local control and avoided surgery, including bronchoplasty, for MEC. Combined treatment of tumor reduction by HFS and PDT of the residual lesion may be an optimal treatment for MEC of the bronchus.
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spelling pubmed-101750292023-05-12 Mucoepidermoid carcinoma cured by a combination of high‐frequency snare and photodynamic therapy: A case report Tamura, Kentaro Uchimura, Keigo Furuse, Hideaki Imabayashi, Tatsuya Matsumoto, Yuji Tsuchida, Takaaki Thorac Cancer Case Reports Mucoepidermoid carcinoma (MEC) is a rare salivary gland tumor, accounting for 0.2% of all lung tumors. The standard treatment for MEC of the primary bronchus is surgery, although intraluminal bronchoscopic treatment has recently become an option. A 68‐year‐old man presented with an asymptomatic bronchial tumor in the right intermediate bronchus. The tumor was resected using a high‐frequency snare (HFS) during bronchoscopy, and the specimen was pathologically diagnosed as low‐grade MEC. A residual lesion was detected in the resected area by autofluorescence imaging. The tumor appeared to be localized within the subepithelial layer without metastases, and photodynamic therapy (PDT) was performed as a local treatment. The patient had no recurrence for 18 months. PDT is effective and safe for patients with centrally located early‐stage lung cancer, but there are few reports of its use for rare tumors, such as MEC. In this case, PDT allowed for local control and avoided surgery, including bronchoplasty, for MEC. Combined treatment of tumor reduction by HFS and PDT of the residual lesion may be an optimal treatment for MEC of the bronchus. John Wiley & Sons Australia, Ltd 2023-03-16 /pmc/articles/PMC10175029/ /pubmed/36929314 http://dx.doi.org/10.1111/1759-7714.14861 Text en © 2023 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Tamura, Kentaro
Uchimura, Keigo
Furuse, Hideaki
Imabayashi, Tatsuya
Matsumoto, Yuji
Tsuchida, Takaaki
Mucoepidermoid carcinoma cured by a combination of high‐frequency snare and photodynamic therapy: A case report
title Mucoepidermoid carcinoma cured by a combination of high‐frequency snare and photodynamic therapy: A case report
title_full Mucoepidermoid carcinoma cured by a combination of high‐frequency snare and photodynamic therapy: A case report
title_fullStr Mucoepidermoid carcinoma cured by a combination of high‐frequency snare and photodynamic therapy: A case report
title_full_unstemmed Mucoepidermoid carcinoma cured by a combination of high‐frequency snare and photodynamic therapy: A case report
title_short Mucoepidermoid carcinoma cured by a combination of high‐frequency snare and photodynamic therapy: A case report
title_sort mucoepidermoid carcinoma cured by a combination of high‐frequency snare and photodynamic therapy: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175029/
https://www.ncbi.nlm.nih.gov/pubmed/36929314
http://dx.doi.org/10.1111/1759-7714.14861
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