Cargando…
Cohort profile update: Tehran cardiometabolic genetic study
The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study that conducts periodic follow-ups. TCGS has created a comprehensive database comprising 20,367 participants born between 1911 and 2015 selected from four main ongoing studies in a family-based longitudinal frame...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175059/ https://www.ncbi.nlm.nih.gov/pubmed/37169991 http://dx.doi.org/10.1007/s10654-023-01008-1 |
_version_ | 1785040167229194240 |
---|---|
author | Daneshpour, Maryam S. Akbarzadeh, Mahdi Lanjanian, Hossein Sedaghati-khayat, Bahar Guity, Kamran Masjoudi, Sajedeh Zahedi, Asiyeh Sadat Moazzam-Jazi, Maryam Bonab, Leila Najd Hassan Shalbafan, Bita Asgarian, Sara Farhood, Goodarz Koli Javanrooh, Niloofar Zarkesh, Maryam Riahi, Parisa Moghaddas, Mohammad Reza Dehkordi, Parvaneh Arbab Ahmadi, Azar Delbarpour Hosseini, Firoozeh Farahani, Sara Jalali Hadaegh, Farzad Mirmiran, Parvin Tehrani, Fahimeh Ramezani Ghanbarian, Arash Pasand, Mohammad Sadegh Fallah Mahboob Amiri, Parisa Valizadeh, Majid Hosseipanah, Farhad Tohidi, Maryam Ghasemi, Asghar Zadeh-Vakili, Azita Piryaei, Mohammad Alamdari, Shahram Khalili, Davood Momenan, Amirabbas Barzin, Maryam Zeinali, Sirous Hedayati, Mehdi Azizi, Fereidoun |
author_facet | Daneshpour, Maryam S. Akbarzadeh, Mahdi Lanjanian, Hossein Sedaghati-khayat, Bahar Guity, Kamran Masjoudi, Sajedeh Zahedi, Asiyeh Sadat Moazzam-Jazi, Maryam Bonab, Leila Najd Hassan Shalbafan, Bita Asgarian, Sara Farhood, Goodarz Koli Javanrooh, Niloofar Zarkesh, Maryam Riahi, Parisa Moghaddas, Mohammad Reza Dehkordi, Parvaneh Arbab Ahmadi, Azar Delbarpour Hosseini, Firoozeh Farahani, Sara Jalali Hadaegh, Farzad Mirmiran, Parvin Tehrani, Fahimeh Ramezani Ghanbarian, Arash Pasand, Mohammad Sadegh Fallah Mahboob Amiri, Parisa Valizadeh, Majid Hosseipanah, Farhad Tohidi, Maryam Ghasemi, Asghar Zadeh-Vakili, Azita Piryaei, Mohammad Alamdari, Shahram Khalili, Davood Momenan, Amirabbas Barzin, Maryam Zeinali, Sirous Hedayati, Mehdi Azizi, Fereidoun |
author_sort | Daneshpour, Maryam S. |
collection | PubMed |
description | The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study that conducts periodic follow-ups. TCGS has created a comprehensive database comprising 20,367 participants born between 1911 and 2015 selected from four main ongoing studies in a family-based longitudinal framework. The study's primary goal is to identify the potential targets for prevention and intervention for non-communicable diseases that may develop in mid-life and late life. TCGS cohort focuses on cardiovascular, endocrine, metabolic abnormalities, cancers, and some inherited diseases. Since 2017, the TCGS cohort has augmented by encoding all health-related complications, including hospitalization outcomes and self-reports according to ICD11 coding, and verifying consanguineous marriage using genetic markers. This research provides an update on the rationale and design of the study, summarizes its findings, and outlines the objectives for precision medicine. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10654-023-01008-1. |
format | Online Article Text |
id | pubmed-10175059 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-101750592023-05-14 Cohort profile update: Tehran cardiometabolic genetic study Daneshpour, Maryam S. Akbarzadeh, Mahdi Lanjanian, Hossein Sedaghati-khayat, Bahar Guity, Kamran Masjoudi, Sajedeh Zahedi, Asiyeh Sadat Moazzam-Jazi, Maryam Bonab, Leila Najd Hassan Shalbafan, Bita Asgarian, Sara Farhood, Goodarz Koli Javanrooh, Niloofar Zarkesh, Maryam Riahi, Parisa Moghaddas, Mohammad Reza Dehkordi, Parvaneh Arbab Ahmadi, Azar Delbarpour Hosseini, Firoozeh Farahani, Sara Jalali Hadaegh, Farzad Mirmiran, Parvin Tehrani, Fahimeh Ramezani Ghanbarian, Arash Pasand, Mohammad Sadegh Fallah Mahboob Amiri, Parisa Valizadeh, Majid Hosseipanah, Farhad Tohidi, Maryam Ghasemi, Asghar Zadeh-Vakili, Azita Piryaei, Mohammad Alamdari, Shahram Khalili, Davood Momenan, Amirabbas Barzin, Maryam Zeinali, Sirous Hedayati, Mehdi Azizi, Fereidoun Eur J Epidemiol Cohort Update The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study that conducts periodic follow-ups. TCGS has created a comprehensive database comprising 20,367 participants born between 1911 and 2015 selected from four main ongoing studies in a family-based longitudinal framework. The study's primary goal is to identify the potential targets for prevention and intervention for non-communicable diseases that may develop in mid-life and late life. TCGS cohort focuses on cardiovascular, endocrine, metabolic abnormalities, cancers, and some inherited diseases. Since 2017, the TCGS cohort has augmented by encoding all health-related complications, including hospitalization outcomes and self-reports according to ICD11 coding, and verifying consanguineous marriage using genetic markers. This research provides an update on the rationale and design of the study, summarizes its findings, and outlines the objectives for precision medicine. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10654-023-01008-1. Springer Netherlands 2023-05-12 2023 /pmc/articles/PMC10175059/ /pubmed/37169991 http://dx.doi.org/10.1007/s10654-023-01008-1 Text en © Springer Nature B.V. 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Cohort Update Daneshpour, Maryam S. Akbarzadeh, Mahdi Lanjanian, Hossein Sedaghati-khayat, Bahar Guity, Kamran Masjoudi, Sajedeh Zahedi, Asiyeh Sadat Moazzam-Jazi, Maryam Bonab, Leila Najd Hassan Shalbafan, Bita Asgarian, Sara Farhood, Goodarz Koli Javanrooh, Niloofar Zarkesh, Maryam Riahi, Parisa Moghaddas, Mohammad Reza Dehkordi, Parvaneh Arbab Ahmadi, Azar Delbarpour Hosseini, Firoozeh Farahani, Sara Jalali Hadaegh, Farzad Mirmiran, Parvin Tehrani, Fahimeh Ramezani Ghanbarian, Arash Pasand, Mohammad Sadegh Fallah Mahboob Amiri, Parisa Valizadeh, Majid Hosseipanah, Farhad Tohidi, Maryam Ghasemi, Asghar Zadeh-Vakili, Azita Piryaei, Mohammad Alamdari, Shahram Khalili, Davood Momenan, Amirabbas Barzin, Maryam Zeinali, Sirous Hedayati, Mehdi Azizi, Fereidoun Cohort profile update: Tehran cardiometabolic genetic study |
title | Cohort profile update: Tehran cardiometabolic genetic study |
title_full | Cohort profile update: Tehran cardiometabolic genetic study |
title_fullStr | Cohort profile update: Tehran cardiometabolic genetic study |
title_full_unstemmed | Cohort profile update: Tehran cardiometabolic genetic study |
title_short | Cohort profile update: Tehran cardiometabolic genetic study |
title_sort | cohort profile update: tehran cardiometabolic genetic study |
topic | Cohort Update |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175059/ https://www.ncbi.nlm.nih.gov/pubmed/37169991 http://dx.doi.org/10.1007/s10654-023-01008-1 |
work_keys_str_mv | AT daneshpourmaryams cohortprofileupdatetehrancardiometabolicgeneticstudy AT akbarzadehmahdi cohortprofileupdatetehrancardiometabolicgeneticstudy AT lanjanianhossein cohortprofileupdatetehrancardiometabolicgeneticstudy AT sedaghatikhayatbahar cohortprofileupdatetehrancardiometabolicgeneticstudy AT guitykamran cohortprofileupdatetehrancardiometabolicgeneticstudy AT masjoudisajedeh cohortprofileupdatetehrancardiometabolicgeneticstudy AT zahediasiyehsadat cohortprofileupdatetehrancardiometabolicgeneticstudy AT moazzamjazimaryam cohortprofileupdatetehrancardiometabolicgeneticstudy AT bonableilanajdhassan cohortprofileupdatetehrancardiometabolicgeneticstudy AT shalbafanbita cohortprofileupdatetehrancardiometabolicgeneticstudy AT asgariansara cohortprofileupdatetehrancardiometabolicgeneticstudy AT farhoodgoodarzkoli cohortprofileupdatetehrancardiometabolicgeneticstudy AT javanroohniloofar cohortprofileupdatetehrancardiometabolicgeneticstudy AT zarkeshmaryam cohortprofileupdatetehrancardiometabolicgeneticstudy AT riahiparisa cohortprofileupdatetehrancardiometabolicgeneticstudy AT moghaddasmohammadreza cohortprofileupdatetehrancardiometabolicgeneticstudy AT dehkordiparvaneharbab cohortprofileupdatetehrancardiometabolicgeneticstudy AT ahmadiazardelbarpour cohortprofileupdatetehrancardiometabolicgeneticstudy AT hosseinifiroozeh cohortprofileupdatetehrancardiometabolicgeneticstudy AT farahanisarajalali cohortprofileupdatetehrancardiometabolicgeneticstudy AT hadaeghfarzad cohortprofileupdatetehrancardiometabolicgeneticstudy AT mirmiranparvin cohortprofileupdatetehrancardiometabolicgeneticstudy AT tehranifahimehramezani cohortprofileupdatetehrancardiometabolicgeneticstudy AT ghanbarianarash cohortprofileupdatetehrancardiometabolicgeneticstudy AT pasandmohammadsadeghfallahmahboob cohortprofileupdatetehrancardiometabolicgeneticstudy AT amiriparisa cohortprofileupdatetehrancardiometabolicgeneticstudy AT valizadehmajid cohortprofileupdatetehrancardiometabolicgeneticstudy AT hosseipanahfarhad cohortprofileupdatetehrancardiometabolicgeneticstudy AT tohidimaryam cohortprofileupdatetehrancardiometabolicgeneticstudy AT ghasemiasghar cohortprofileupdatetehrancardiometabolicgeneticstudy AT zadehvakiliazita cohortprofileupdatetehrancardiometabolicgeneticstudy AT piryaeimohammad cohortprofileupdatetehrancardiometabolicgeneticstudy AT alamdarishahram cohortprofileupdatetehrancardiometabolicgeneticstudy AT khalilidavood cohortprofileupdatetehrancardiometabolicgeneticstudy AT momenanamirabbas cohortprofileupdatetehrancardiometabolicgeneticstudy AT barzinmaryam cohortprofileupdatetehrancardiometabolicgeneticstudy AT zeinalisirous cohortprofileupdatetehrancardiometabolicgeneticstudy AT hedayatimehdi cohortprofileupdatetehrancardiometabolicgeneticstudy AT azizifereidoun cohortprofileupdatetehrancardiometabolicgeneticstudy |