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author Daneshpour, Maryam S.
Akbarzadeh, Mahdi
Lanjanian, Hossein
Sedaghati-khayat, Bahar
Guity, Kamran
Masjoudi, Sajedeh
Zahedi, Asiyeh Sadat
Moazzam-Jazi, Maryam
Bonab, Leila Najd Hassan
Shalbafan, Bita
Asgarian, Sara
Farhood, Goodarz Koli
Javanrooh, Niloofar
Zarkesh, Maryam
Riahi, Parisa
Moghaddas, Mohammad Reza
Dehkordi, Parvaneh Arbab
Ahmadi, Azar Delbarpour
Hosseini, Firoozeh
Farahani, Sara Jalali
Hadaegh, Farzad
Mirmiran, Parvin
Tehrani, Fahimeh Ramezani
Ghanbarian, Arash
Pasand, Mohammad Sadegh Fallah Mahboob
Amiri, Parisa
Valizadeh, Majid
Hosseipanah, Farhad
Tohidi, Maryam
Ghasemi, Asghar
Zadeh-Vakili, Azita
Piryaei, Mohammad
Alamdari, Shahram
Khalili, Davood
Momenan, Amirabbas
Barzin, Maryam
Zeinali, Sirous
Hedayati, Mehdi
Azizi, Fereidoun
author_facet Daneshpour, Maryam S.
Akbarzadeh, Mahdi
Lanjanian, Hossein
Sedaghati-khayat, Bahar
Guity, Kamran
Masjoudi, Sajedeh
Zahedi, Asiyeh Sadat
Moazzam-Jazi, Maryam
Bonab, Leila Najd Hassan
Shalbafan, Bita
Asgarian, Sara
Farhood, Goodarz Koli
Javanrooh, Niloofar
Zarkesh, Maryam
Riahi, Parisa
Moghaddas, Mohammad Reza
Dehkordi, Parvaneh Arbab
Ahmadi, Azar Delbarpour
Hosseini, Firoozeh
Farahani, Sara Jalali
Hadaegh, Farzad
Mirmiran, Parvin
Tehrani, Fahimeh Ramezani
Ghanbarian, Arash
Pasand, Mohammad Sadegh Fallah Mahboob
Amiri, Parisa
Valizadeh, Majid
Hosseipanah, Farhad
Tohidi, Maryam
Ghasemi, Asghar
Zadeh-Vakili, Azita
Piryaei, Mohammad
Alamdari, Shahram
Khalili, Davood
Momenan, Amirabbas
Barzin, Maryam
Zeinali, Sirous
Hedayati, Mehdi
Azizi, Fereidoun
author_sort Daneshpour, Maryam S.
collection PubMed
description The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study that conducts periodic follow-ups. TCGS has created a comprehensive database comprising 20,367 participants born between 1911 and 2015 selected from four main ongoing studies in a family-based longitudinal framework. The study's primary goal is to identify the potential targets for prevention and intervention for non-communicable diseases that may develop in mid-life and late life. TCGS cohort focuses on cardiovascular, endocrine, metabolic abnormalities, cancers, and some inherited diseases. Since 2017, the TCGS cohort has augmented by encoding all health-related complications, including hospitalization outcomes and self-reports according to ICD11 coding, and verifying consanguineous marriage using genetic markers. This research provides an update on the rationale and design of the study, summarizes its findings, and outlines the objectives for precision medicine. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10654-023-01008-1.
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spelling pubmed-101750592023-05-14 Cohort profile update: Tehran cardiometabolic genetic study Daneshpour, Maryam S. Akbarzadeh, Mahdi Lanjanian, Hossein Sedaghati-khayat, Bahar Guity, Kamran Masjoudi, Sajedeh Zahedi, Asiyeh Sadat Moazzam-Jazi, Maryam Bonab, Leila Najd Hassan Shalbafan, Bita Asgarian, Sara Farhood, Goodarz Koli Javanrooh, Niloofar Zarkesh, Maryam Riahi, Parisa Moghaddas, Mohammad Reza Dehkordi, Parvaneh Arbab Ahmadi, Azar Delbarpour Hosseini, Firoozeh Farahani, Sara Jalali Hadaegh, Farzad Mirmiran, Parvin Tehrani, Fahimeh Ramezani Ghanbarian, Arash Pasand, Mohammad Sadegh Fallah Mahboob Amiri, Parisa Valizadeh, Majid Hosseipanah, Farhad Tohidi, Maryam Ghasemi, Asghar Zadeh-Vakili, Azita Piryaei, Mohammad Alamdari, Shahram Khalili, Davood Momenan, Amirabbas Barzin, Maryam Zeinali, Sirous Hedayati, Mehdi Azizi, Fereidoun Eur J Epidemiol Cohort Update The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study that conducts periodic follow-ups. TCGS has created a comprehensive database comprising 20,367 participants born between 1911 and 2015 selected from four main ongoing studies in a family-based longitudinal framework. The study's primary goal is to identify the potential targets for prevention and intervention for non-communicable diseases that may develop in mid-life and late life. TCGS cohort focuses on cardiovascular, endocrine, metabolic abnormalities, cancers, and some inherited diseases. Since 2017, the TCGS cohort has augmented by encoding all health-related complications, including hospitalization outcomes and self-reports according to ICD11 coding, and verifying consanguineous marriage using genetic markers. This research provides an update on the rationale and design of the study, summarizes its findings, and outlines the objectives for precision medicine. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10654-023-01008-1. Springer Netherlands 2023-05-12 2023 /pmc/articles/PMC10175059/ /pubmed/37169991 http://dx.doi.org/10.1007/s10654-023-01008-1 Text en © Springer Nature B.V. 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Cohort Update
Daneshpour, Maryam S.
Akbarzadeh, Mahdi
Lanjanian, Hossein
Sedaghati-khayat, Bahar
Guity, Kamran
Masjoudi, Sajedeh
Zahedi, Asiyeh Sadat
Moazzam-Jazi, Maryam
Bonab, Leila Najd Hassan
Shalbafan, Bita
Asgarian, Sara
Farhood, Goodarz Koli
Javanrooh, Niloofar
Zarkesh, Maryam
Riahi, Parisa
Moghaddas, Mohammad Reza
Dehkordi, Parvaneh Arbab
Ahmadi, Azar Delbarpour
Hosseini, Firoozeh
Farahani, Sara Jalali
Hadaegh, Farzad
Mirmiran, Parvin
Tehrani, Fahimeh Ramezani
Ghanbarian, Arash
Pasand, Mohammad Sadegh Fallah Mahboob
Amiri, Parisa
Valizadeh, Majid
Hosseipanah, Farhad
Tohidi, Maryam
Ghasemi, Asghar
Zadeh-Vakili, Azita
Piryaei, Mohammad
Alamdari, Shahram
Khalili, Davood
Momenan, Amirabbas
Barzin, Maryam
Zeinali, Sirous
Hedayati, Mehdi
Azizi, Fereidoun
Cohort profile update: Tehran cardiometabolic genetic study
title Cohort profile update: Tehran cardiometabolic genetic study
title_full Cohort profile update: Tehran cardiometabolic genetic study
title_fullStr Cohort profile update: Tehran cardiometabolic genetic study
title_full_unstemmed Cohort profile update: Tehran cardiometabolic genetic study
title_short Cohort profile update: Tehran cardiometabolic genetic study
title_sort cohort profile update: tehran cardiometabolic genetic study
topic Cohort Update
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175059/
https://www.ncbi.nlm.nih.gov/pubmed/37169991
http://dx.doi.org/10.1007/s10654-023-01008-1
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