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The role of STING signaling in central nervous system infection and neuroinflammatory disease

The cyclic guanosine monophosphate–adenosine monophosphate (GMP-AMP) synthase-Stimulator of Interferon Genes (cGAS-STING) pathway is a critical innate immune mechanism for detecting the presence of double-stranded DNA (dsDNA) and prompting a robust immune response. Canonical cGAS-STING activation oc...

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Detalles Bibliográficos
Autores principales: Fritsch, Lauren E., Kelly, Colin, Pickrell, Alicia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175194/
https://www.ncbi.nlm.nih.gov/pubmed/36632700
http://dx.doi.org/10.1002/wsbm.1597

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