Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson’s disease

Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are progressive neurodegenerative diseases characterized by the accumulation of misfolded α-synuclein in the form of Lewy pathology. While most cases are sporadic, there are rare genetic mutations that cause disease and more common variant...

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Detalles Bibliográficos
Autores principales: Leyns, Cheryl E. G., Prigent, Alice, Beezhold, Brenna, Yao, Lihang, Hatcher, Nathan G., Tao, Peining, Kang, John, Suh, EunRan, Van Deerlin, Vivianna M., Trojanowski, John Q., Lee, Virginia M. Y., Kennedy, Matthew E., Fell, Matthew J., Henderson, Michael X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175254/
https://www.ncbi.nlm.nih.gov/pubmed/37169750
http://dx.doi.org/10.1038/s41531-023-00517-w

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