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An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization

Medical Assisted Reproduction proved its efficacy to treat the vast majority forms of infertility. One of the key procedures in this treatment is the selection and transfer of the embryo with the highest developmental potential. To assess this potential, clinical embryologists routinely work with st...

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Autores principales: Kromp, Florian, Wagner, Raphael, Balaban, Basak, Cottin, Véronique, Cuevas-Saiz, Irene, Schachner, Clara, Fancsovits, Peter, Fawzy, Mohamed, Fischer, Lukas, Findikli, Necati, Kovačič, Borut, Ljiljak, Dejan, Martínez-Rodero, Iris, Parmegiani, Lodovico, Shebl, Omar, Min, Xie, Ebner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175281/
https://www.ncbi.nlm.nih.gov/pubmed/37169791
http://dx.doi.org/10.1038/s41597-023-02182-3
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author Kromp, Florian
Wagner, Raphael
Balaban, Basak
Cottin, Véronique
Cuevas-Saiz, Irene
Schachner, Clara
Fancsovits, Peter
Fawzy, Mohamed
Fischer, Lukas
Findikli, Necati
Kovačič, Borut
Ljiljak, Dejan
Martínez-Rodero, Iris
Parmegiani, Lodovico
Shebl, Omar
Min, Xie
Ebner, Thomas
author_facet Kromp, Florian
Wagner, Raphael
Balaban, Basak
Cottin, Véronique
Cuevas-Saiz, Irene
Schachner, Clara
Fancsovits, Peter
Fawzy, Mohamed
Fischer, Lukas
Findikli, Necati
Kovačič, Borut
Ljiljak, Dejan
Martínez-Rodero, Iris
Parmegiani, Lodovico
Shebl, Omar
Min, Xie
Ebner, Thomas
author_sort Kromp, Florian
collection PubMed
description Medical Assisted Reproduction proved its efficacy to treat the vast majority forms of infertility. One of the key procedures in this treatment is the selection and transfer of the embryo with the highest developmental potential. To assess this potential, clinical embryologists routinely work with static images (morphological assessment) or short video sequences (time-lapse annotation). Recently, Artificial Intelligence models were utilized to support the embryo selection procedure. Even though they have proven their great potential in different in vitro fertilization settings, there is still considerable room for improvement. To support the advancement of algorithms in this research field, we built a dataset consisting of static blastocyst images and additional annotations. As such, Gardner criteria annotations, depicting a morphological blastocyst rating scheme, and collected clinical parameters are provided. The presented dataset is intended to be used to train deep learning models on static morphological images to predict Gardner’s criteria and clinical outcomes such as live birth. A benchmark of human expert’s performance in annotating Gardner criteria is provided.
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spelling pubmed-101752812023-05-13 An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization Kromp, Florian Wagner, Raphael Balaban, Basak Cottin, Véronique Cuevas-Saiz, Irene Schachner, Clara Fancsovits, Peter Fawzy, Mohamed Fischer, Lukas Findikli, Necati Kovačič, Borut Ljiljak, Dejan Martínez-Rodero, Iris Parmegiani, Lodovico Shebl, Omar Min, Xie Ebner, Thomas Sci Data Data Descriptor Medical Assisted Reproduction proved its efficacy to treat the vast majority forms of infertility. One of the key procedures in this treatment is the selection and transfer of the embryo with the highest developmental potential. To assess this potential, clinical embryologists routinely work with static images (morphological assessment) or short video sequences (time-lapse annotation). Recently, Artificial Intelligence models were utilized to support the embryo selection procedure. Even though they have proven their great potential in different in vitro fertilization settings, there is still considerable room for improvement. To support the advancement of algorithms in this research field, we built a dataset consisting of static blastocyst images and additional annotations. As such, Gardner criteria annotations, depicting a morphological blastocyst rating scheme, and collected clinical parameters are provided. The presented dataset is intended to be used to train deep learning models on static morphological images to predict Gardner’s criteria and clinical outcomes such as live birth. A benchmark of human expert’s performance in annotating Gardner criteria is provided. Nature Publishing Group UK 2023-05-11 /pmc/articles/PMC10175281/ /pubmed/37169791 http://dx.doi.org/10.1038/s41597-023-02182-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Data Descriptor
Kromp, Florian
Wagner, Raphael
Balaban, Basak
Cottin, Véronique
Cuevas-Saiz, Irene
Schachner, Clara
Fancsovits, Peter
Fawzy, Mohamed
Fischer, Lukas
Findikli, Necati
Kovačič, Borut
Ljiljak, Dejan
Martínez-Rodero, Iris
Parmegiani, Lodovico
Shebl, Omar
Min, Xie
Ebner, Thomas
An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization
title An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization
title_full An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization
title_fullStr An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization
title_full_unstemmed An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization
title_short An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization
title_sort annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175281/
https://www.ncbi.nlm.nih.gov/pubmed/37169791
http://dx.doi.org/10.1038/s41597-023-02182-3
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