Vesicular glutamate transporters are H(+)-anion exchangers that operate at variable stoichiometry

Vesicular glutamate transporters accumulate glutamate in synaptic vesicles, where they also function as a major Cl(-) efflux pathway. Here we combine heterologous expression and cellular electrophysiology with mathematical modeling to understand the mechanisms underlying this dual function of rat VG...

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Detalles Bibliográficos
Autores principales: Kolen, Bettina, Borghans, Bart, Kortzak, Daniel, Lugo, Victor, Hannack, Cora, Guzman, Raul E., Ullah, Ghanim, Fahlke, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175566/
https://www.ncbi.nlm.nih.gov/pubmed/37169755
http://dx.doi.org/10.1038/s41467-023-38340-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175566/
https://www.ncbi.nlm.nih.gov/pubmed/37169755
http://dx.doi.org/10.1038/s41467-023-38340-9

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