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Vesicular glutamate transporters are H(+)-anion exchangers that operate at variable stoichiometry
Vesicular glutamate transporters accumulate glutamate in synaptic vesicles, where they also function as a major Cl(-) efflux pathway. Here we combine heterologous expression and cellular electrophysiology with mathematical modeling to understand the mechanisms underlying this dual function of rat VG...
Autores principales: | Kolen, Bettina, Borghans, Bart, Kortzak, Daniel, Lugo, Victor, Hannack, Cora, Guzman, Raul E., Ullah, Ghanim, Fahlke, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175566/ https://www.ncbi.nlm.nih.gov/pubmed/37169755 http://dx.doi.org/10.1038/s41467-023-38340-9 |
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