Striatal spatial heterogeneity, clustering, and white matter association of GFAP(+) astrocytes in a mouse model of Huntington’s disease

INTRODUCTION: Huntington’s disease (HD) is a neurodegenerative disease that primarily affects the striatum, a brain region that controls movement and some forms of cognition. Neuronal dysfunction and loss in HD is accompanied by increased astrocyte density and astrocyte pathology. Astrocytes are a h...

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Detalles Bibliográficos
Autores principales: Brown, Taylor G., Thayer, Mackenzie N., VanTreeck, Jillian G., Zarate, Nicole, Hart, Damyan W., Heilbronner, Sarah, Gomez-Pastor, Rocio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175581/
https://www.ncbi.nlm.nih.gov/pubmed/37187609
http://dx.doi.org/10.3389/fncel.2023.1094503

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