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Integration of optic flow into the sky compass network in the brain of the desert locust

Flexible orientation through any environment requires a sense of current relative heading that is updated based on self-motion. Global external cues originating from the sky or the earth‘s magnetic field and local cues provide a reference frame for the sense of direction. Locally, optic flow may inf...

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Autores principales: Zittrell, Frederick, Pabst, Kathrin, Carlomagno, Elena, Rosner, Ronny, Pegel, Uta, Endres, Dominik M., Homberg, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175609/
https://www.ncbi.nlm.nih.gov/pubmed/37187914
http://dx.doi.org/10.3389/fncir.2023.1111310
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author Zittrell, Frederick
Pabst, Kathrin
Carlomagno, Elena
Rosner, Ronny
Pegel, Uta
Endres, Dominik M.
Homberg, Uwe
author_facet Zittrell, Frederick
Pabst, Kathrin
Carlomagno, Elena
Rosner, Ronny
Pegel, Uta
Endres, Dominik M.
Homberg, Uwe
author_sort Zittrell, Frederick
collection PubMed
description Flexible orientation through any environment requires a sense of current relative heading that is updated based on self-motion. Global external cues originating from the sky or the earth‘s magnetic field and local cues provide a reference frame for the sense of direction. Locally, optic flow may inform about turning maneuvers, travel speed and covered distance. The central complex in the insect brain is associated with orientation behavior and largely acts as a navigation center. Visual information from global celestial cues and local landmarks are integrated in the central complex to form an internal representation of current heading. However, it is less clear how optic flow is integrated into the central-complex network. We recorded intracellularly from neurons in the locust central complex while presenting lateral grating patterns that simulated translational and rotational motion to identify these sites of integration. Certain types of central-complex neurons were sensitive to optic-flow stimulation independent of the type and direction of simulated motion. Columnar neurons innervating the noduli, paired central-complex substructures, were tuned to the direction of simulated horizontal turns. Modeling the connectivity of these neurons with a system of proposed compass neurons can account for rotation-direction specific shifts in the activity profile in the central complex corresponding to turn direction. Our model is similar but not identical to the mechanisms proposed for angular velocity integration in the navigation compass of the fly Drosophila.
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spelling pubmed-101756092023-05-13 Integration of optic flow into the sky compass network in the brain of the desert locust Zittrell, Frederick Pabst, Kathrin Carlomagno, Elena Rosner, Ronny Pegel, Uta Endres, Dominik M. Homberg, Uwe Front Neural Circuits Neuroscience Flexible orientation through any environment requires a sense of current relative heading that is updated based on self-motion. Global external cues originating from the sky or the earth‘s magnetic field and local cues provide a reference frame for the sense of direction. Locally, optic flow may inform about turning maneuvers, travel speed and covered distance. The central complex in the insect brain is associated with orientation behavior and largely acts as a navigation center. Visual information from global celestial cues and local landmarks are integrated in the central complex to form an internal representation of current heading. However, it is less clear how optic flow is integrated into the central-complex network. We recorded intracellularly from neurons in the locust central complex while presenting lateral grating patterns that simulated translational and rotational motion to identify these sites of integration. Certain types of central-complex neurons were sensitive to optic-flow stimulation independent of the type and direction of simulated motion. Columnar neurons innervating the noduli, paired central-complex substructures, were tuned to the direction of simulated horizontal turns. Modeling the connectivity of these neurons with a system of proposed compass neurons can account for rotation-direction specific shifts in the activity profile in the central complex corresponding to turn direction. Our model is similar but not identical to the mechanisms proposed for angular velocity integration in the navigation compass of the fly Drosophila. Frontiers Media S.A. 2023-04-28 /pmc/articles/PMC10175609/ /pubmed/37187914 http://dx.doi.org/10.3389/fncir.2023.1111310 Text en Copyright © 2023 Zittrell, Pabst, Carlomagno, Rosner, Pegel, Endres and Homberg. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Zittrell, Frederick
Pabst, Kathrin
Carlomagno, Elena
Rosner, Ronny
Pegel, Uta
Endres, Dominik M.
Homberg, Uwe
Integration of optic flow into the sky compass network in the brain of the desert locust
title Integration of optic flow into the sky compass network in the brain of the desert locust
title_full Integration of optic flow into the sky compass network in the brain of the desert locust
title_fullStr Integration of optic flow into the sky compass network in the brain of the desert locust
title_full_unstemmed Integration of optic flow into the sky compass network in the brain of the desert locust
title_short Integration of optic flow into the sky compass network in the brain of the desert locust
title_sort integration of optic flow into the sky compass network in the brain of the desert locust
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175609/
https://www.ncbi.nlm.nih.gov/pubmed/37187914
http://dx.doi.org/10.3389/fncir.2023.1111310
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