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Mapping of exogenous choline uptake and metabolism in rat glioblastoma using deuterium metabolic imaging (DMI)

INTRODUCTION: There is a lack of robust metabolic imaging techniques that can be routinely applied to characterize lesions in patients with brain tumors. Here we explore in an animal model of glioblastoma the feasibility to detect uptake and metabolism of deuterated choline and describe the tumor-to...

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Detalles Bibliográficos
Autores principales: Ip, Kevan L., Thomas, Monique A., Behar, Kevin L., de Graaf, Robin A., De Feyter, Henk M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175635/
https://www.ncbi.nlm.nih.gov/pubmed/37187610
http://dx.doi.org/10.3389/fncel.2023.1130816