Cargando…

Single cell analysis of the localization of the hematopoietic stem cells within the bone marrow architecture identifies niche-specific proliferation dynamics

INTRODUCTION: Hematopoietic stem cells (HSC) reside in the bone marrow (BM) in specialized niches which provide support for their self-replication and differentiation into the blood cells. Recently, numerous studies using sophisticated molecular and microscopic technology have provided snap-shots in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mazzarini, Maria, Arciprete, Francesca, Picconi, Orietta, Valeri, Mauro, Verachi, Paola, Martelli, Fabrizio, Migliaccio, Anna Rita, Falchi, Mario, Zingariello, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175646/ https://www.ncbi.nlm.nih.gov/pubmed/37188088 http://dx.doi.org/10.3389/fmed.2023.1166758

Ejemplares similares

Resident Self-Tissue of Proinflammatory Cytokines Rather Than Their Systemic Levels Correlates with Development of Myelofibrosis in Gata1(low) Mice
por: Zingariello, Maria, et al.
Publicado: (2022)

Role of β1 integrin in thrombocytopoiesis
por: Mazzarini, Maria, et al.
Publicado: (2021)

GATA1-defective immune-megakaryocytes as possible drivers of idiopathic pulmonary fibrosis
por: Gobbo, Francesca, et al.
Publicado: (2023)

hGATA1 Under the Control of a μLCR/β-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced by the Gata1 ( low ) Mutation in Mice
por: Martelli, Fabrizio, et al.
Publicado: (2021)

Phosphoproteomic Landscaping Identifies Non-canonical cKIT Signaling in Polycythemia Vera Erythroid Progenitors
por: Federici, Giulia, et al.
Publicado: (2019)

Shared and Distinctive Ultrastructural Abnormalities Expressed by Megakaryocytes in Bone Marrow and Spleen From Patients With Myelofibrosis
por: Zingariello, Maria, et al.
Publicado: (2020)

Patients with hypercortisolemic Cushing disease possess a distinct class of hematopoietic progenitor cells leading to erythrocytosis
por: Varricchio, Lilian, et al.
Publicado: (2022)

TGF-β1 protein trap AVID200 beneficially affects hematopoiesis and bone marrow fibrosis in myelofibrosis
por: Varricchio, Lilian, et al.
Publicado: (2021)

Bone Marrow Niches of Hematopoietic Stem and Progenitor Cells
por: Kandarakov, Oleg, et al.
Publicado: (2022)

Bone Marrow Niches for Hematopoietic Stem Cells and Immune Cells
por: Sugiyama, Tatsuki, et al.
Publicado: (2012)

The Hematopoietic Bone Marrow Niche Ecosystem
por: Fröbel, Julia, et al.
Publicado: (2021)

Neoplastic Bone Marrow Niche: Hematopoietic and Mesenchymal Stem Cells
por: Saki, Najmaldin, et al.
Publicado: (2011)

Bone Marrow Vascular Niche: Home for Hematopoietic Stem Cells
por: He, Ningning, et al.
Publicado: (2014)

Megakaryocyte Contribution to Bone Marrow Fibrosis: many Arrows in the Quiver
por: Malara, Alessandro, et al.
Publicado: (2018)

Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow
por: Mansour, Anna, et al.
Publicado: (2012)

The Bone Marrow Microenvironment as Niche Retreats for Hematopoietic and Leukemic Stem Cells
por: Nwajei, Felix, et al.
Publicado: (2013)

Bone Marrow Adipocytes: The Enigmatic Components of the Hematopoietic Stem Cell Niche
por: Cuminetti, Vincent, et al.
Publicado: (2019)

Murine Bone Marrow Niches from Hematopoietic Stem Cells to B Cells
por: Aurrand-Lions, Michel, et al.
Publicado: (2018)

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche
por: Maryanovich, Maria, et al.
Publicado: (2018)

Role of the Osteoblast Lineage in the Bone Marrow Hematopoietic Niches
por: Wu, Joy Y, et al.
Publicado: (2009)

Young donor hematopoietic stem cells revitalize aged or damaged bone marrow niche by transdifferentiating into functional niche cells
por: Yuan, Na, et al.
Publicado: (2023)

Mobilization of hematopoietic stem cells from the bone marrow niche to the blood compartment
por: Hoggatt, Jonathan, et al.
Publicado: (2011)

Limited rejuvenation of aged hematopoietic stem cells in young bone marrow niche
por: Kuribayashi, Wakako, et al.
Publicado: (2020)

Alterations in Hematopoietic and Mesenchymal Stromal Cell Components of the Osteopetrotic Bone Marrow Niche
por: Zeytin, Inci Cevher, et al.
Publicado: (2022)

Hematopoietic Stem Cell Niche During Homeostasis, Malignancy, and Bone Marrow Transplantation
por: Man, Yan, et al.
Publicado: (2021)

TGFBI Expressed by Bone Marrow Niche Cells and Hematopoietic Stem and Progenitor Cells Regulates Hematopoiesis
por: Klamer, Sofieke E., et al.
Publicado: (2018)

Osteopontin is An Important Regulative Component of the Fetal Bone Marrow Hematopoietic Stem Cell Niche
por: Cao, Huimin, et al.
Publicado: (2019)

The cellular composition and function of the bone marrow niche after allogeneic hematopoietic cell transplantation
por: Peci, Flavia, et al.
Publicado: (2022)

Cellular niches for hematopoietic stem cells in bone marrow under normal and malignant conditions
por: Omatsu, Yoshiki
Publicado: (2023)

The molecular signature of therapeutic mesenchymal stem cells exposes the architecture of the hematopoietic stem cell niche synapse
por: Pedemonte, Enrico, et al.
Publicado: (2007)

Loss of ASXL1 in the bone marrow niche dysregulates hematopoietic stem and progenitor cell fates
por: Zhang, Peng, et al.
Publicado: (2018)

ICAM-1 Deficiency in the Bone Marrow Niche Impairs Quiescence and Repopulation of Hematopoietic Stem Cells
por: Liu, Yu-feng, et al.
Publicado: (2018)

Inferring Gene Networks in Bone Marrow Hematopoietic Stem Cell-Supporting Stromal Niche Populations
por: Desterke, Christophe, et al.
Publicado: (2020)

Gap Junctions in the Bone Marrow Lympho-Hematopoietic Stem Cell Niche, Leukemia Progression, and Chemoresistance
por: Singh, Abhishek K., et al.
Publicado: (2020)

The Dynamic Interface Between the Bone Marrow Vascular Niche and Hematopoietic Stem Cells in Myeloid Malignancy
por: Mosteo, Laura, et al.
Publicado: (2021)

Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture
por: Lu, Yanfang, et al.
Publicado: (2021)

PTPN13 and β-Catenin Regulate the Quiescence of Hematopoietic Stem Cells and Their Interaction with the Bone Marrow Niche
por: López-Ruano, Guillermo, et al.
Publicado: (2015)

Inhibition of SRC-mediated integrin signaling in bone marrow niche enhances hematopoietic stem cell function
por: Roy, Irene Mariam, et al.
Publicado: (2022)

Niche-modulated and niche-modulating genes in bone marrow cells
por: Cohen, Y, et al.
Publicado: (2012)

Hematopoietic Cell Kinase (HCK) Is a Player of the Crosstalk Between Hematopoietic Cells and Bone Marrow Niche Through CXCL12/CXCR4 Axis
por: Roversi, Fernanda Marconi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oue7h4a748hrj0l4hp4sp48on4