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Intersection of nanomaterials and organoids technology in biomedicine

Organoids are stem cell-derived, self-organizing, 3D structures. Compared to the conventional 2D cell culture method, 3D cultured organoids contain a variety of cell types that can form functional “micro-organs” and can be used to simulate the occurrence process and physiological pathological state...

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Autores principales: Shen, Chen, Zhang, Zi-jian, Li, Xiao-xue, Huang, Yun-peng, Wang, Yong-xiang, Zhou, Hui, Xiong, Li, Wen, Yu, Zou, Heng, Liu, Zhong-tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175666/
https://www.ncbi.nlm.nih.gov/pubmed/37187755
http://dx.doi.org/10.3389/fimmu.2023.1172262
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author Shen, Chen
Zhang, Zi-jian
Li, Xiao-xue
Huang, Yun-peng
Wang, Yong-xiang
Zhou, Hui
Xiong, Li
Wen, Yu
Zou, Heng
Liu, Zhong-tao
author_facet Shen, Chen
Zhang, Zi-jian
Li, Xiao-xue
Huang, Yun-peng
Wang, Yong-xiang
Zhou, Hui
Xiong, Li
Wen, Yu
Zou, Heng
Liu, Zhong-tao
author_sort Shen, Chen
collection PubMed
description Organoids are stem cell-derived, self-organizing, 3D structures. Compared to the conventional 2D cell culture method, 3D cultured organoids contain a variety of cell types that can form functional “micro-organs” and can be used to simulate the occurrence process and physiological pathological state of organ tissues more effectively. Nanomaterials (NMs) are becoming indispensable in the development of novel organoids. Understanding the application of nanomaterials in organoid construction can, therefore, provide researchers with ideas for the development of novel organoids. Here, we discuss the application status of NMs in various organoid culture systems and the research direction of NMs combined with organoids in the biomedical field.
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spelling pubmed-101756662023-05-13 Intersection of nanomaterials and organoids technology in biomedicine Shen, Chen Zhang, Zi-jian Li, Xiao-xue Huang, Yun-peng Wang, Yong-xiang Zhou, Hui Xiong, Li Wen, Yu Zou, Heng Liu, Zhong-tao Front Immunol Immunology Organoids are stem cell-derived, self-organizing, 3D structures. Compared to the conventional 2D cell culture method, 3D cultured organoids contain a variety of cell types that can form functional “micro-organs” and can be used to simulate the occurrence process and physiological pathological state of organ tissues more effectively. Nanomaterials (NMs) are becoming indispensable in the development of novel organoids. Understanding the application of nanomaterials in organoid construction can, therefore, provide researchers with ideas for the development of novel organoids. Here, we discuss the application status of NMs in various organoid culture systems and the research direction of NMs combined with organoids in the biomedical field. Frontiers Media S.A. 2023-04-28 /pmc/articles/PMC10175666/ /pubmed/37187755 http://dx.doi.org/10.3389/fimmu.2023.1172262 Text en Copyright © 2023 Shen, Zhang, Li, Huang, Wang, Zhou, Xiong, Wen, Zou and Liu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Shen, Chen
Zhang, Zi-jian
Li, Xiao-xue
Huang, Yun-peng
Wang, Yong-xiang
Zhou, Hui
Xiong, Li
Wen, Yu
Zou, Heng
Liu, Zhong-tao
Intersection of nanomaterials and organoids technology in biomedicine
title Intersection of nanomaterials and organoids technology in biomedicine
title_full Intersection of nanomaterials and organoids technology in biomedicine
title_fullStr Intersection of nanomaterials and organoids technology in biomedicine
title_full_unstemmed Intersection of nanomaterials and organoids technology in biomedicine
title_short Intersection of nanomaterials and organoids technology in biomedicine
title_sort intersection of nanomaterials and organoids technology in biomedicine
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175666/
https://www.ncbi.nlm.nih.gov/pubmed/37187755
http://dx.doi.org/10.3389/fimmu.2023.1172262
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