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The PRAK-NRF2 axis promotes the differentiation of Th17 cells by mediating the redox homeostasis and glycolysis

Oxidative stress is a key feature in both chronic inflammation and cancer. P38 regulated/activated protein kinase (PRAK) deficiency can cause functional disorders in neutrophils and macrophages under high oxidative stress, but the precise mechanisms by which PRAK regulates reactive oxygen species (R...

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Detalles Bibliográficos
Autores principales:	Zhao, Ziheng, Wang, Yan, Gao, Yuhan, Ju, Yurong, Zhao, Ye, Wu, Zhaofei, Gao, Shuaixin, Zhang, Boyang, Pang, Xuewen, Zhang, Yu, Wang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175746/ https://www.ncbi.nlm.nih.gov/pubmed/37126714 http://dx.doi.org/10.1073/pnas.2212613120

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