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Angiotensin II receptor inhibition ameliorates liver fibrosis and enhances hepatocellular carcinoma infiltration by effector T cells

Although viral hepatocellular carcinoma (HCC) is declining, nonviral HCC, which often is the end stage of nonalcoholic or alcoholic steatohepatitis (NASH, ASH), is on an upward trajectory. Immune checkpoint inhibitors (ICIs) that block the T cell inhibitory receptor PD-1 were approved for treatment...

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Detalles Bibliográficos
Autores principales: Gu, Li, Zhu, Yahui, Lee, Maiya, Nguyen, Albert, Ryujin, Nicolas T., Huang, Jian Yu, Pandit, Shusil K., Chamseddine, Shadi, Xiao, Lianchun, Mohamed, Yehia I., Kaseb, Ahmed O., Karin, Michael, Shalapour, Shabnam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175751/
https://www.ncbi.nlm.nih.gov/pubmed/37126700
http://dx.doi.org/10.1073/pnas.2300706120