Cargando…

Towards realistic privacy-preserving deep learning over encrypted medical data

Cardiovascular disease supposes a substantial fraction of healthcare systems. The invisible nature of these pathologies demands solutions that enable remote monitoring and tracking. Deep Learning (DL) has arisen as a solution in many fields, and in healthcare, multiple successful applications exist...

Descripción completa

Detalles Bibliográficos
Autores principales: Cabrero-Holgueras, José, Pastrana, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175772/
https://www.ncbi.nlm.nih.gov/pubmed/37187785
http://dx.doi.org/10.3389/fcvm.2023.1117360
_version_ 1785040283931508736
author Cabrero-Holgueras, José
Pastrana, Sergio
author_facet Cabrero-Holgueras, José
Pastrana, Sergio
author_sort Cabrero-Holgueras, José
collection PubMed
description Cardiovascular disease supposes a substantial fraction of healthcare systems. The invisible nature of these pathologies demands solutions that enable remote monitoring and tracking. Deep Learning (DL) has arisen as a solution in many fields, and in healthcare, multiple successful applications exist for image enhancement and health outside hospitals. However, the computational requirements and the need for large-scale datasets limit DL. Thus, we often offload computation onto server infrastructure, and various Machine-Learning-as-a-Service (MLaaS) platforms emerged from this need. These enable the conduction of heavy computations in a cloud infrastructure, usually equipped with high-performance computing servers. Unfortunately, the technical barriers persist in healthcare ecosystems since sending sensitive data (e.g., medical records or personally identifiable information) to third-party servers involves privacy and security concerns with legal and ethical implications. In the scope of Deep Learning for Healthcare to improve cardiovascular health, Homomorphic Encryption (HE) is a promising tool to enable secure, private, and legal health outside hospitals. Homomorphic Encryption allows for privacy-preserving computations over encrypted data, thus preserving the privacy of the processed information. Efficient HE requires structural optimizations to perform the complex computation of the internal layers. One such optimization is Packed Homomorphic Encryption (PHE), which encodes multiple elements on a single ciphertext, allowing for efficient Single Instruction over Multiple Data (SIMD) operations. However, using PHE in DL circuits is not straightforward, and it demands new algorithms and data encoding, which existing literature has not adequately addressed. To fill this gap, in this work, we elaborate on novel algorithms to adapt the linear algebra operations of DL layers to PHE. Concretely, we focus on Convolutional Neural Networks. We provide detailed descriptions and insights into the different algorithms and efficient inter-layer data format conversion mechanisms. We formally analyze the complexity of the algorithms in terms of performance metrics and provide guidelines and recommendations for adapting architectures that deal with private data. Furthermore, we confirm the theoretical analysis with practical experimentation. Among other conclusions, we prove that our new algorithms speed up the processing of convolutional layers compared to the existing proposals.
format Online
Article
Text
id pubmed-10175772
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-101757722023-05-13 Towards realistic privacy-preserving deep learning over encrypted medical data Cabrero-Holgueras, José Pastrana, Sergio Front Cardiovasc Med Cardiovascular Medicine Cardiovascular disease supposes a substantial fraction of healthcare systems. The invisible nature of these pathologies demands solutions that enable remote monitoring and tracking. Deep Learning (DL) has arisen as a solution in many fields, and in healthcare, multiple successful applications exist for image enhancement and health outside hospitals. However, the computational requirements and the need for large-scale datasets limit DL. Thus, we often offload computation onto server infrastructure, and various Machine-Learning-as-a-Service (MLaaS) platforms emerged from this need. These enable the conduction of heavy computations in a cloud infrastructure, usually equipped with high-performance computing servers. Unfortunately, the technical barriers persist in healthcare ecosystems since sending sensitive data (e.g., medical records or personally identifiable information) to third-party servers involves privacy and security concerns with legal and ethical implications. In the scope of Deep Learning for Healthcare to improve cardiovascular health, Homomorphic Encryption (HE) is a promising tool to enable secure, private, and legal health outside hospitals. Homomorphic Encryption allows for privacy-preserving computations over encrypted data, thus preserving the privacy of the processed information. Efficient HE requires structural optimizations to perform the complex computation of the internal layers. One such optimization is Packed Homomorphic Encryption (PHE), which encodes multiple elements on a single ciphertext, allowing for efficient Single Instruction over Multiple Data (SIMD) operations. However, using PHE in DL circuits is not straightforward, and it demands new algorithms and data encoding, which existing literature has not adequately addressed. To fill this gap, in this work, we elaborate on novel algorithms to adapt the linear algebra operations of DL layers to PHE. Concretely, we focus on Convolutional Neural Networks. We provide detailed descriptions and insights into the different algorithms and efficient inter-layer data format conversion mechanisms. We formally analyze the complexity of the algorithms in terms of performance metrics and provide guidelines and recommendations for adapting architectures that deal with private data. Furthermore, we confirm the theoretical analysis with practical experimentation. Among other conclusions, we prove that our new algorithms speed up the processing of convolutional layers compared to the existing proposals. Frontiers Media S.A. 2023-04-28 /pmc/articles/PMC10175772/ /pubmed/37187785 http://dx.doi.org/10.3389/fcvm.2023.1117360 Text en © 2023 Cabrero-Holgueras and Pastrana. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Cabrero-Holgueras, José
Pastrana, Sergio
Towards realistic privacy-preserving deep learning over encrypted medical data
title Towards realistic privacy-preserving deep learning over encrypted medical data
title_full Towards realistic privacy-preserving deep learning over encrypted medical data
title_fullStr Towards realistic privacy-preserving deep learning over encrypted medical data
title_full_unstemmed Towards realistic privacy-preserving deep learning over encrypted medical data
title_short Towards realistic privacy-preserving deep learning over encrypted medical data
title_sort towards realistic privacy-preserving deep learning over encrypted medical data
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175772/
https://www.ncbi.nlm.nih.gov/pubmed/37187785
http://dx.doi.org/10.3389/fcvm.2023.1117360
work_keys_str_mv AT cabreroholguerasjose towardsrealisticprivacypreservingdeeplearningoverencryptedmedicaldata
AT pastranasergio towardsrealisticprivacypreservingdeeplearningoverencryptedmedicaldata