Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis

Intestinal bile acids play an essential role in the Clostridioides difficile lifecycle having been shown in vitro to modulate various aspects of pathogenesis, including spore germination, vegetative growth, and more recently the action of the primary virulence determinant, TcdB. Here, we investigate...

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Detalles Bibliográficos
Autores principales: Icho, Simoun, Ward, Jennifer S., Tam, John, Kociolek, Larry K., Theriot, Casey M., Melnyk, Roman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175849/
https://www.ncbi.nlm.nih.gov/pubmed/37126691
http://dx.doi.org/10.1073/pnas.2301252120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175849/
https://www.ncbi.nlm.nih.gov/pubmed/37126691
http://dx.doi.org/10.1073/pnas.2301252120

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