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Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis
Intestinal bile acids play an essential role in the Clostridioides difficile lifecycle having been shown in vitro to modulate various aspects of pathogenesis, including spore germination, vegetative growth, and more recently the action of the primary virulence determinant, TcdB. Here, we investigate...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175849/ https://www.ncbi.nlm.nih.gov/pubmed/37126691 http://dx.doi.org/10.1073/pnas.2301252120 |