CTLA4-Ig protects tacrolimus-induced oxidative stress via inhibiting the AKT/FOXO3 signaling pathway in rats

BACKGROUND/AIMS: Although the conversion from tacrolimus (TAC) to cytotoxic T-lymphocyte-associated antigen 4-immunoglobulin (CTLA4-Ig) is effective in reducing TAC-induced nephrotoxicity, it remains unclear whether CTLA4-Ig has a direct effect on TAC-induced renal injury. In this study, we evaluate...

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Detalles Bibliográficos
Autores principales: Jin, Long, Shen, Nan, Wen, Xinyu, Wang, Weidong, Lim, Sun Woo, Yang, Chul Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175874/
https://www.ncbi.nlm.nih.gov/pubmed/37157174
http://dx.doi.org/10.3904/kjim.2022.293

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