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The Optimal Dosing Regimen of Super Bioavailable Itraconazole in Obesity: An Experimental Rat Model Study

Background Obesity may alter tissue distribution and clearance of several drugs, especially lipophilic ones. Itraconazole, a lipophilic drug, has been recently introduced in a super-bioavailable formulation (SB-ITZ) for the treatment of dermatophytosis. Evidence regarding optimal dosing of SB-ITZ in...

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Detalles Bibliográficos
Autores principales: Jain, Gaurav K, Chitnis, Kruttika R, Singhal, Payal, Mahadkar, Namrata, Dhoot, Dhiraj, Barkate, Hanmant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175893/
https://www.ncbi.nlm.nih.gov/pubmed/37187635
http://dx.doi.org/10.7759/cureus.37462