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The Optimal Dosing Regimen of Super Bioavailable Itraconazole in Obesity: An Experimental Rat Model Study
Background Obesity may alter tissue distribution and clearance of several drugs, especially lipophilic ones. Itraconazole, a lipophilic drug, has been recently introduced in a super-bioavailable formulation (SB-ITZ) for the treatment of dermatophytosis. Evidence regarding optimal dosing of SB-ITZ in...
Autores principales: | Jain, Gaurav K, Chitnis, Kruttika R, Singhal, Payal, Mahadkar, Namrata, Dhoot, Dhiraj, Barkate, Hanmant |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175893/ https://www.ncbi.nlm.nih.gov/pubmed/37187635 http://dx.doi.org/10.7759/cureus.37462 |
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