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Activation of the urotensin-II receptor by remdesivir induces cardiomyocyte dysfunction

Remdesivir is an antiviral drug used for COVID-19 treatment worldwide. Cardiovascular side effects have been associated with remdesivir; however, the underlying molecular mechanism remains unknown. Here, we performed a large-scale G-protein-coupled receptor screening in combination with structural m...

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Detalles Bibliográficos
Autores principales: Ogawa, Akiko, Ohira, Seiya, Kato, Yuri, Ikuta, Tatsuya, Yanagida, Shota, Mi, Xinya, Ishii, Yukina, Kanda, Yasunari, Nishida, Motohiro, Inoue, Asuka, Wei, Fan-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175918/
https://www.ncbi.nlm.nih.gov/pubmed/37173432
http://dx.doi.org/10.1038/s42003-023-04888-x

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