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Response to primary chemoradiotherapy of locally advanced oropharyngeal carcinoma is determined by the degree of cytotoxic T cell infiltration within tumor cell aggregates
BACKGROUND: Effective anti-tumor immune responses are mediated by T cells and require organized, spatially coordinated interactions within the tumor microenvironment (TME). Understanding coordinated T-cell-behavior and deciphering mechanisms of radiotherapy resistance mediated by tumor stem cells wi...
Autores principales: | Haist, Maximilian, Kaufmann, Justus, Kur, Ivan-Maximiliano, Zimmer, Stefanie, Grabbe, Stephan, Schmidberger, Heinz, Weigert, Andreas, Mayer, Arnulf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175951/ https://www.ncbi.nlm.nih.gov/pubmed/37187729 http://dx.doi.org/10.3389/fimmu.2023.1070203 |
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