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Population pharmacokinetics of intramuscular recombinant Erwinia chrysanthemi asparaginase (JZP458) in patients with acute lymphoblastic leukemia

JZP458 is a recombinant Erwinia chrysanthemi asparaginase for patients with acute lymphoblastic leukemia (ALL)/lymphoblastic lymphoma (LBL) who have developed hypersensitivity to Escherichia coli–derived asparaginases. A population pharmacokinetic (PopPK) model was developed for intramuscular (i.m.)...

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Detalles Bibliográficos
Autores principales:	Lin, Tong, Whigham, Tajhia, Fernando, Indrasiri, Choi, Mi Rim, Wang, Qi, Silverman, Jeffrey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175977/ https://www.ncbi.nlm.nih.gov/pubmed/36929533 http://dx.doi.org/10.1111/cts.13499

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