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The heterogeneity of asymmetric tau distribution is associated with an early age at onset and poor prognosis in Alzheimer’s disease

PURPOSE: Left-right asymmetry, an important feature of brain development, has been implicated in neurodegenerative diseases, although it’s less discussed in typical Alzheimer’s disease (AD). We sought to investigate whether asymmetric tau deposition plays a potential role in AD heterogeneity. METHOD...

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Detalles Bibliográficos
Autores principales: Lu, Jiaying, Zhang, Zhengwei, Wu, Ping, Liang, Xiaoniu, Zhang, Huiwei, Hong, Jimin, Clement, Christoph, Yen, Tzu-Chen, Ding, Saineng, Wang, Min, Xiao, Zhenxu, Rominger, Axel, Shi, Kuangyu, Guan, Yihui, Zuo, Chuantao, Zhao, Qianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176076/
https://www.ncbi.nlm.nih.gov/pubmed/37137254
http://dx.doi.org/10.1016/j.nicl.2023.103416