The eIF4EBP-eIF4E axis regulates CD4(+) T cell differentiation through modulation of T cell activation and metabolism

CD4(+) T cells are critical for adaptive immunity, differentiating into distinct effector and regulatory subsets. Although the transcriptional programs underlying their differentiation are known, recent research has highlighted the importance of mRNA translation in determining protein abundance. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Istomine, Roman, Al-Aubodah, Tho-Alfakar, Alvarez, Fernando, Smith, Jacob A., Wagner, Carston, Piccirillo, Ciriaco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176268/
https://www.ncbi.nlm.nih.gov/pubmed/37187701
http://dx.doi.org/10.1016/j.isci.2023.106683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176268/
https://www.ncbi.nlm.nih.gov/pubmed/37187701
http://dx.doi.org/10.1016/j.isci.2023.106683

Ejemplares similares