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The eIF4EBP-eIF4E axis regulates CD4(+) T cell differentiation through modulation of T cell activation and metabolism
CD4(+) T cells are critical for adaptive immunity, differentiating into distinct effector and regulatory subsets. Although the transcriptional programs underlying their differentiation are known, recent research has highlighted the importance of mRNA translation in determining protein abundance. We...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176268/ https://www.ncbi.nlm.nih.gov/pubmed/37187701 http://dx.doi.org/10.1016/j.isci.2023.106683 |