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SINEUP non-coding RNA activity depends on specific N6-methyladenosine nucleotides
SINEUPs are natural and synthetic antisense long non-coding RNAs (lncRNAs) selectively enhancing target mRNAs translation by increasing their association with polysomes. This activity requires two RNA domains: an embedded inverted SINEB2 element acting as effector domain, and an antisense region, th...
Autores principales: | Pierattini, Bianca, D’Agostino, Sabrina, Bon, Carlotta, Peruzzo, Omar, Alendar, Andrej, Codino, Azzurra, Ros, Gloria, Persichetti, Francesca, Sanges, Remo, Carninci, Piero, Santoro, Claudio, Espinoza, Stefano, Valentini, Paola, Pandolfini, Luca, Gustincich, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176434/ https://www.ncbi.nlm.nih.gov/pubmed/37187707 http://dx.doi.org/10.1016/j.omtn.2023.04.002 |
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