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SINEUP non-coding RNA activity depends on specific N6-methyladenosine nucleotides

SINEUPs are natural and synthetic antisense long non-coding RNAs (lncRNAs) selectively enhancing target mRNAs translation by increasing their association with polysomes. This activity requires two RNA domains: an embedded inverted SINEB2 element acting as effector domain, and an antisense region, th...

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Detalles Bibliográficos
Autores principales: Pierattini, Bianca, D’Agostino, Sabrina, Bon, Carlotta, Peruzzo, Omar, Alendar, Andrej, Codino, Azzurra, Ros, Gloria, Persichetti, Francesca, Sanges, Remo, Carninci, Piero, Santoro, Claudio, Espinoza, Stefano, Valentini, Paola, Pandolfini, Luca, Gustincich, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176434/
https://www.ncbi.nlm.nih.gov/pubmed/37187707
http://dx.doi.org/10.1016/j.omtn.2023.04.002

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