Cargando…

Identifying the intervention mechanisms of polydatin in hyperuricemia model rats by using UHPLC-Q-Exactive Orbitrap mass spectroscopy metabonomic approach

INTRODUCTION: Polydatin is a biologically active compound found in mulberries, grapes, and Polygonum cuspidatum, and it has uric acid-lowering effects. However, its urate-lowering effects and the molecular mechanisms underlying its function require further study. METHODS: In this study, a hyperurice...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ge, Xueli, Su, Zhenguo, Wang, Yuhao, Zhao, Xue, Hou, Kaifei, Zheng, Shuna, Zeng, Pengjiao, Shi, Zhongqi, Hu, Senhao, Wang, Yuqing, Zhou, Mengchen, Zhang, Jiayu, Li, Xiulian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176606/ https://www.ncbi.nlm.nih.gov/pubmed/37187876 http://dx.doi.org/10.3389/fnut.2023.1117460

Ejemplares similares

NMR-Based Metabonomic Study Reveals Intervention Effects of Polydatin on Potassium Oxonate-Induced Hyperuricemia in Rats
por: Han, Bin, et al.
Publicado: (2020)

The Metabolites and Mechanism Analysis of Genistin against Hyperlipidemia via the UHPLC-Q-Exactive Orbitrap Mass Spectrometer and Metabolomics
por: Li, Zhe, et al.
Publicado: (2023)

Identification of the metabolites of isochlorogenic acid A in rats by UHPLC-Q-Exactive Orbitrap MS
por: Gong, Kaiyan, et al.
Publicado: (2020)

Stepwise Targeted Matching Strategy for Comprehensive Profiling of Xanthohumol Metabolites In Vivo and In Vitro Using UHPLC-Q-Exactive Orbitrap Mass Spectrometer
por: Yuan, Xiaoqing, et al.
Publicado: (2023)

Identification of Chemical Composition of Leaves and Flowers from Paeonia rockii by UHPLC-Q-Exactive Orbitrap HRMS
por: Li, Jinhua, et al.
Publicado: (2016)

Mycotoxin Occurrence and Risk Assessment in Gluten-Free Pasta through UHPLC-Q-Exactive Orbitrap MS
por: Tolosa, Josefa, et al.
Publicado: (2021)

Qualitative Analysis of Multiple Phytochemical Compounds in Tojapride Based on UHPLC Q-Exactive Orbitrap Mass Spectrometry
por: Zhang, Liying, et al.
Publicado: (2022)

Phytochemistry and Antioxidant Activities of the Rhizome and Radix of Millettia speciosa Based on UHPLC-Q-Exactive Orbitrap-MS
por: Zhang, Jianguang, et al.
Publicado: (2022)

Comprehensive characterization of multiple components of Ziziphus jujuba Mill using UHPLC‐Q‐Exactive Orbitrap Mass Spectrometers
por: Qin, Shi‐han, et al.
Publicado: (2022)

Optimization of the extraction process and metabonomics analysis of uric acid-reducing active substances from Gymnadenia R.Br. and its protective effect on hyperuricemia zebrafish
por: Chen, Tianrong, et al.
Publicado: (2022)

Identification of the Constituents of Percutaneous Absorption from Duhaldea nervosa Based on UHPLC-Q-Exactive Orbitrap MS and Microdialysis Technique
por: Liu, Lianghong, et al.
Publicado: (2019)

Systematic Screening of Chemical Constituents in the Traditional Chinese Medicine Arnebiae Radix by UHPLC-Q-Exactive Orbitrap Mass Spectrometry
por: Zhu, Lian, et al.
Publicado: (2022)

Identification and Quantification of Chlorogenic Acids from the Root Bark of Acanthopanax gracilistylus by UHPLC-Q-Exactive Orbitrap Mass Spectrometry
por: Yang, Jianbo, et al.
Publicado: (2022)

Structural Identification of Impurities in Pioglitazone Hydrochloride Preparations by 2D-UHPLC-Q-Exactive Orbitrap HRMS and Their Toxicity Prediction
por: Zhang, Dandan, et al.
Publicado: (2023)

Systematically Exploring the Chemical Ingredients and Absorbed Constituents of Polygonum capitatum in Hyperuricemia Rat Plasma Using UHPLC-Q-Orbitrap HRMS
por: Guan, Huanyu, et al.
Publicado: (2022)

High-Throughput Identification of Organic Compounds from Polygoni Multiflori Radix Praeparata (Zhiheshouwu) by UHPLC-Q-Exactive Orbitrap-MS
por: Wang, Shaoyun, et al.
Publicado: (2021)

Biological Activities of Selected Plants and Detection of Bioactive Compounds from Ardisia elliptica Using UHPLC-Q-Exactive Orbitrap Mass Spectrometry
por: Wong, Pei Lou, et al.
Publicado: (2020)

Screening of Quality Markers During the Processing of Reynoutria multiflora Based on the UHPLC-Q-Exactive Plus Orbitrap MS/MS Metabolomic Method
por: Bai, Junqi, et al.
Publicado: (2021)

Rapid Identification of Constituents in Cephalanthus tetrandrus (Roxb.) Ridsd. et Badh. F. Using UHPLC-Q-Exactive Orbitrap Mass Spectrometry
por: Tang, Su-Nv, et al.
Publicado: (2022)

Rapid Characterization and Action Mechanism of the Antidiabetic Effect of Diospyros lotus L Using UHPLC-Q-Exactive Orbitrap MS and Network Pharmacology
por: Qin, Shihan, et al.
Publicado: (2022)

Stepwise Diagnostic Product Ions Filtering Strategy for Rapid Discovery of Diterpenoids in Scutellaria barbata Based on UHPLC-Q-Exactive-Orbitrap-MS
por: Zhou, Xinhua, et al.
Publicado: (2022)

A Systematic Method for the Identification of Aporphine Alkaloid Constituents in Sabia schumanniana Diels Using UHPLC-Q-Exactive Orbitrap/Mass Spectrometry
por: E, Shuai, et al.
Publicado: (2022)

Diagnostic Fragment-Ion-Based for Rapid Identification of Chlorogenic Acids Derivatives in Inula cappa Using UHPLC-Q-Exactive Orbitrap Mass Spectrometry
por: Peng, Jie, et al.
Publicado: (2021)

Rapid Identification and Systematic Mechanism of Flavonoids from Potentilla freyniana Bornm. Based on UHPLC-Q-Exactive Orbitrap Mass Spectrometry and Network Pharmacology
por: Cai, Wei, et al.
Publicado: (2021)

Simultaneous determination of eight analytes of Fuzheng Huayu recipe in beagle dog plasma by UHPLC–Q/exactive Orbitrap HRMS and its application to toxicokinetics
por: Wang, Yu‐Lin, et al.
Publicado: (2022)

Metabolites Identification and Mechanism Prediction of Neobavaisoflavone In Vitro and In Vivo of Rats through UHPLC-Q-Exactive Plus Orbitrap MS Integrated Network Pharmacology
por: Li, Linlin, et al.
Publicado: (2022)

UHPLC-Q-Exactive Orbitrap MS/MS-Based Untargeted Metabolomics and Molecular Networking Reveal the Differential Chemical Constituents of the Bulbs and Flowers of Fritillaria thunbergii
por: Li, Xin, et al.
Publicado: (2022)

Metabolite Profiling for Typization of “Rucola della Piana del Sele” (PGI), Eruca sativa, through UHPLC-Q-Exactive-Orbitrap-MS/MS Analysis
por: Crescenzi, Maria Assunta, et al.
Publicado: (2023)

Comparing the Profiles of Raw and Cooked Donkey Meat by Metabonomics and Lipidomics Assessment
por: Li, Mengmeng, et al.
Publicado: (2022)

Identification and mechanism prediction of mulberroside A metabolites in vivo and in vitro of rats using an integrated strategy of UHPLC-Q-Exactive Plus Orbitrap MS and network pharmacology
por: Zhang, Xiao, et al.
Publicado: (2022)

Pharmacokinetics and Metabolism Research of Shenkang Injection in Rats Based on UHPLC-MS/MS and UHPLC-Q-Orbitrap HRMS
por: Jiang, Xiaofang, et al.
Publicado: (2020)

Exploring ECD on a Benchtop Q Exactive Orbitrap Mass Spectrometer
por: Fort, Kyle L., et al.
Publicado: (2017)

The Analytical Strategy of “Ion Induction and Deduction Based on Net-Hubs” for the Comprehensive Characterization of Naringenin Metabolites In Vivo and In Vitro Using a UHPLC-Q-Exactive Orbitrap Mass Spectrometer
por: Cui, Yi-Fang, et al.
Publicado: (2022)

Rapid Screening and Identification of Daidzein Metabolites in Rats Based on UHPLC-LTQ-Orbitrap Mass Spectrometry Coupled with Data-Mining Technologies
por: Zhao, Wenjing, et al.
Publicado: (2018)

Rapid Identification of 3,6′-Disinapoyl Sucrose Metabolites in Alzheimer’s Disease Model Mice Using UHPLC–Orbitrap Mass Spectrometry
por: Yuan, Jiaqi, et al.
Publicado: (2021)

Identification of Phenolic Compounds from Hancornia speciosa (Apocynaceae) Leaves by UHPLC Orbitrap-HRMS
por: Bastos, Katherine Xavier, et al.
Publicado: (2017)

In Vivo Antihypertensive Activity and UHPLC-Orbitrap-HRMS Profiling of Cuphea ignea A. DC.
por: Ismail, Walaa M., et al.
Publicado: (2022)

The Interaction Between Dietary Fructose and Gut Microbiota in Hyperuricemia and Gout
por: Fang, Xin-yu, et al.
Publicado: (2022)

Chemical profiling and quantification of XueBiJing injection, a systematic quality control strategy using UHPLC-Q Exactive hybrid quadrupole-orbitrap high-resolution mass spectrometry
por: Sun, Zhi, et al.
Publicado: (2017)

Polydatin, A Glycoside of Resveratrol, Is Better Than Resveratrol in Alleviating Non-alcoholic Fatty Liver Disease in Mice Fed a High-Fructose Diet
por: Zhao, Guangshan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_plsqa47acdbdi4vcgf928d0f1q