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Transjugular intrahepatic portosystemic shunt in decompensated cirrhotic patients in a tertiary hospital in southern Brazil
OBJECTIVE: The aim of the present study was to evaluate the outcomes of cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt. METHODS: A retrospective longitudinal observational study was carried out evaluating 38 cirrhotic patients undergoing transjugular intrahepatic portosy...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Médica Brasileira
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176653/ https://www.ncbi.nlm.nih.gov/pubmed/37075438 http://dx.doi.org/10.1590/1806-9282.20220944 |
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author | Titton, Carolina Moro Torikachvili, Marcio Rêgo, Heloísa M. C. Medronha, Eduardo F. Ziemiecki, Enio Ribas, Carolina Ceratti, Carlos Germano de Mattos, Angelo Alves Tovo, Cristiane Valle |
author_facet | Titton, Carolina Moro Torikachvili, Marcio Rêgo, Heloísa M. C. Medronha, Eduardo F. Ziemiecki, Enio Ribas, Carolina Ceratti, Carlos Germano de Mattos, Angelo Alves Tovo, Cristiane Valle |
author_sort | Titton, Carolina Moro |
collection | PubMed |
description | OBJECTIVE: The aim of the present study was to evaluate the outcomes of cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt. METHODS: A retrospective longitudinal observational study was carried out evaluating 38 cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt. The outcomes were evaluated in an outpatient follow-up period of 3 months. The assumed significance level was 5%. RESULTS: The indications for transjugular intrahepatic portosystemic shunt were refractory ascites in 21 (55.3%), variceal hemorrhage in 13 (34.2%), and hydrothorax in 4 (10.5%) patients. There was development of hepatic encephalopathy in 10 (35.7%) patients after transjugular intrahepatic portosystemic shunt. From the 21 patients with refractory ascites, resolution was observed in 1 (3.1%) patient, and in 16 (50.0%) patients, there was ascites control. Regarding transjugular intrahepatic portosystemic shunt after variceal bleeding, 10 (76.9%) patients remained without new bleeding or hospitalizations in the follow-up period. The global survival in the follow-up period in patients with and without hepatic encephalopathy was 60 vs. 82%, respectively (p=0.032). CONCLUSION: Transjugular intrahepatic portosystemic shunt can be considered in decompensated cirrhotic patients; however, the development of hepatic encephalopathy which can shorten survival should be focused. |
format | Online Article Text |
id | pubmed-10176653 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Associação Médica Brasileira |
record_format | MEDLINE/PubMed |
spelling | pubmed-101766532023-05-13 Transjugular intrahepatic portosystemic shunt in decompensated cirrhotic patients in a tertiary hospital in southern Brazil Titton, Carolina Moro Torikachvili, Marcio Rêgo, Heloísa M. C. Medronha, Eduardo F. Ziemiecki, Enio Ribas, Carolina Ceratti, Carlos Germano de Mattos, Angelo Alves Tovo, Cristiane Valle Rev Assoc Med Bras (1992) Original Article OBJECTIVE: The aim of the present study was to evaluate the outcomes of cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt. METHODS: A retrospective longitudinal observational study was carried out evaluating 38 cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt. The outcomes were evaluated in an outpatient follow-up period of 3 months. The assumed significance level was 5%. RESULTS: The indications for transjugular intrahepatic portosystemic shunt were refractory ascites in 21 (55.3%), variceal hemorrhage in 13 (34.2%), and hydrothorax in 4 (10.5%) patients. There was development of hepatic encephalopathy in 10 (35.7%) patients after transjugular intrahepatic portosystemic shunt. From the 21 patients with refractory ascites, resolution was observed in 1 (3.1%) patient, and in 16 (50.0%) patients, there was ascites control. Regarding transjugular intrahepatic portosystemic shunt after variceal bleeding, 10 (76.9%) patients remained without new bleeding or hospitalizations in the follow-up period. The global survival in the follow-up period in patients with and without hepatic encephalopathy was 60 vs. 82%, respectively (p=0.032). CONCLUSION: Transjugular intrahepatic portosystemic shunt can be considered in decompensated cirrhotic patients; however, the development of hepatic encephalopathy which can shorten survival should be focused. Associação Médica Brasileira 2023-04-14 /pmc/articles/PMC10176653/ /pubmed/37075438 http://dx.doi.org/10.1590/1806-9282.20220944 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Titton, Carolina Moro Torikachvili, Marcio Rêgo, Heloísa M. C. Medronha, Eduardo F. Ziemiecki, Enio Ribas, Carolina Ceratti, Carlos Germano de Mattos, Angelo Alves Tovo, Cristiane Valle Transjugular intrahepatic portosystemic shunt in decompensated cirrhotic patients in a tertiary hospital in southern Brazil |
title | Transjugular intrahepatic portosystemic shunt in decompensated cirrhotic patients in a tertiary hospital in southern Brazil |
title_full | Transjugular intrahepatic portosystemic shunt in decompensated cirrhotic patients in a tertiary hospital in southern Brazil |
title_fullStr | Transjugular intrahepatic portosystemic shunt in decompensated cirrhotic patients in a tertiary hospital in southern Brazil |
title_full_unstemmed | Transjugular intrahepatic portosystemic shunt in decompensated cirrhotic patients in a tertiary hospital in southern Brazil |
title_short | Transjugular intrahepatic portosystemic shunt in decompensated cirrhotic patients in a tertiary hospital in southern Brazil |
title_sort | transjugular intrahepatic portosystemic shunt in decompensated cirrhotic patients in a tertiary hospital in southern brazil |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176653/ https://www.ncbi.nlm.nih.gov/pubmed/37075438 http://dx.doi.org/10.1590/1806-9282.20220944 |
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