_version_ 1785040475328086016
author LaBarbera, Kelsie M.
Sheline, Yvette I.
Izzo, Nicholas J.
Yuede, Carla M.
Waybright, Lora
Yurko, Raymond
Edwards, Hannah M.
Gardiner, Woodrow D.
Blennow, Kaj
Zetterberg, Henrik
Börjesson-Hanson, Anne
Morgan, Roger
Davis, Charles S.
Guttendorf, Robert J.
Schneider, Lon S.
DeKosky, Steven
LeVine, Harry
Grundman, Michael
Caggiano, Anthony O.
Cirrito, John R.
Catalano, Susan M.
Hamby, Mary E.
author_facet LaBarbera, Kelsie M.
Sheline, Yvette I.
Izzo, Nicholas J.
Yuede, Carla M.
Waybright, Lora
Yurko, Raymond
Edwards, Hannah M.
Gardiner, Woodrow D.
Blennow, Kaj
Zetterberg, Henrik
Börjesson-Hanson, Anne
Morgan, Roger
Davis, Charles S.
Guttendorf, Robert J.
Schneider, Lon S.
DeKosky, Steven
LeVine, Harry
Grundman, Michael
Caggiano, Anthony O.
Cirrito, John R.
Catalano, Susan M.
Hamby, Mary E.
author_sort LaBarbera, Kelsie M.
collection PubMed
description
format Online
Article
Text
id pubmed-10176668
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-101766682023-05-13 A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter LaBarbera, Kelsie M. Sheline, Yvette I. Izzo, Nicholas J. Yuede, Carla M. Waybright, Lora Yurko, Raymond Edwards, Hannah M. Gardiner, Woodrow D. Blennow, Kaj Zetterberg, Henrik Börjesson-Hanson, Anne Morgan, Roger Davis, Charles S. Guttendorf, Robert J. Schneider, Lon S. DeKosky, Steven LeVine, Harry Grundman, Michael Caggiano, Anthony O. Cirrito, John R. Catalano, Susan M. Hamby, Mary E. Transl Neurodegener Letter BioMed Central 2023-05-12 /pmc/articles/PMC10176668/ /pubmed/37173791 http://dx.doi.org/10.1186/s40035-023-00358-w Text en © The Author(s) 2023, corrected publication 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Letter
LaBarbera, Kelsie M.
Sheline, Yvette I.
Izzo, Nicholas J.
Yuede, Carla M.
Waybright, Lora
Yurko, Raymond
Edwards, Hannah M.
Gardiner, Woodrow D.
Blennow, Kaj
Zetterberg, Henrik
Börjesson-Hanson, Anne
Morgan, Roger
Davis, Charles S.
Guttendorf, Robert J.
Schneider, Lon S.
DeKosky, Steven
LeVine, Harry
Grundman, Michael
Caggiano, Anthony O.
Cirrito, John R.
Catalano, Susan M.
Hamby, Mary E.
A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter
title A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter
title_full A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter
title_fullStr A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter
title_full_unstemmed A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter
title_short A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter
title_sort phase 1b randomized clinical trial of ct1812 to measure aβ oligomer displacement in alzheimer’s disease using an indwelling csf catheter
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176668/
https://www.ncbi.nlm.nih.gov/pubmed/37173791
http://dx.doi.org/10.1186/s40035-023-00358-w
work_keys_str_mv AT labarberakelsiem aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT shelineyvettei aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT izzonicholasj aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT yuedecarlam aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT waybrightlora aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT yurkoraymond aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT edwardshannahm aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT gardinerwoodrowd aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT blennowkaj aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT zetterberghenrik aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT borjessonhansonanne aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT morganroger aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT davischarless aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT guttendorfrobertj aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT schneiderlons aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT dekoskysteven aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT levineharry aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT grundmanmichael aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT caggianoanthonyo aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT cirritojohnr aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT catalanosusanm aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT hambymarye aphase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT labarberakelsiem phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT shelineyvettei phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT izzonicholasj phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT yuedecarlam phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT waybrightlora phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT yurkoraymond phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT edwardshannahm phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT gardinerwoodrowd phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT blennowkaj phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT zetterberghenrik phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT borjessonhansonanne phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT morganroger phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT davischarless phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT guttendorfrobertj phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT schneiderlons phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT dekoskysteven phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT levineharry phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT grundmanmichael phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT caggianoanthonyo phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT cirritojohnr phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT catalanosusanm phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter
AT hambymarye phase1brandomizedclinicaltrialofct1812tomeasureaboligomerdisplacementinalzheimersdiseaseusinganindwellingcsfcatheter