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Unusual Clinical Manifestations of Thyroid Carcinoma

Thyroid cancer is considered the most common endocrine malignancy, with the most frequent presentation of differentiated thyroid cancer being a neck swelling or an incidental finding of a thyroid nodule on imaging. In this case series, we describe three cases of thyroid cancer with unusual clinical...

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Autores principales: Brijmohan, Sharmela, Elsheikh, Marwa, Hemmings, Chelsey B, Rastogi, Natasha, Schultz, Atara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176757/
https://www.ncbi.nlm.nih.gov/pubmed/37187653
http://dx.doi.org/10.7759/cureus.37474
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author Brijmohan, Sharmela
Elsheikh, Marwa
Hemmings, Chelsey B
Rastogi, Natasha
Schultz, Atara
author_facet Brijmohan, Sharmela
Elsheikh, Marwa
Hemmings, Chelsey B
Rastogi, Natasha
Schultz, Atara
author_sort Brijmohan, Sharmela
collection PubMed
description Thyroid cancer is considered the most common endocrine malignancy, with the most frequent presentation of differentiated thyroid cancer being a neck swelling or an incidental finding of a thyroid nodule on imaging. In this case series, we describe three cases of thyroid cancer with unusual clinical manifestations. The first case describes a patient who underwent parathyroidectomy for primary hyperparathyroidism and was found to have papillary thyroid cancer on a cervical lymph node biopsy. While this may be coincidental, the literature raises the question of whether there may be an association. The second case describes a patient who presents with a suspicious thyroid nodule and was subsequently diagnosed with follicular thyroid cancer on biopsy. This raises the question of performing thyroidectomy early in patients with a suspicious thyroid nodule but a false negative biopsy. The third case describes a patient with a scalp lesion found to have poorly differentiated thyroid carcinoma, a rare presentation of this form of cancer.
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spelling pubmed-101767572023-05-13 Unusual Clinical Manifestations of Thyroid Carcinoma Brijmohan, Sharmela Elsheikh, Marwa Hemmings, Chelsey B Rastogi, Natasha Schultz, Atara Cureus Endocrinology/Diabetes/Metabolism Thyroid cancer is considered the most common endocrine malignancy, with the most frequent presentation of differentiated thyroid cancer being a neck swelling or an incidental finding of a thyroid nodule on imaging. In this case series, we describe three cases of thyroid cancer with unusual clinical manifestations. The first case describes a patient who underwent parathyroidectomy for primary hyperparathyroidism and was found to have papillary thyroid cancer on a cervical lymph node biopsy. While this may be coincidental, the literature raises the question of whether there may be an association. The second case describes a patient who presents with a suspicious thyroid nodule and was subsequently diagnosed with follicular thyroid cancer on biopsy. This raises the question of performing thyroidectomy early in patients with a suspicious thyroid nodule but a false negative biopsy. The third case describes a patient with a scalp lesion found to have poorly differentiated thyroid carcinoma, a rare presentation of this form of cancer. Cureus 2023-04-12 /pmc/articles/PMC10176757/ /pubmed/37187653 http://dx.doi.org/10.7759/cureus.37474 Text en Copyright © 2023, Brijmohan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Brijmohan, Sharmela
Elsheikh, Marwa
Hemmings, Chelsey B
Rastogi, Natasha
Schultz, Atara
Unusual Clinical Manifestations of Thyroid Carcinoma
title Unusual Clinical Manifestations of Thyroid Carcinoma
title_full Unusual Clinical Manifestations of Thyroid Carcinoma
title_fullStr Unusual Clinical Manifestations of Thyroid Carcinoma
title_full_unstemmed Unusual Clinical Manifestations of Thyroid Carcinoma
title_short Unusual Clinical Manifestations of Thyroid Carcinoma
title_sort unusual clinical manifestations of thyroid carcinoma
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176757/
https://www.ncbi.nlm.nih.gov/pubmed/37187653
http://dx.doi.org/10.7759/cureus.37474
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