Rapid cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area, 2012 to June 2022

Whole genome sequencing data of 874 Escherichia coli isolates carrying bla (NDM-5) from 13 European Union/European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and an increasing frequency of detection. Nearly a thi...

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Detalles Bibliográficos
Autores principales: Linkevicius, Marius, Bonnin, Rémy A, Alm, Erik, Svartström, Olov, Apfalter, Petra, Hartl, Rainer, Hasman, Henrik, Roer, Louise, Räisänen, Kati, Dortet, Laurent, Pfennigwerth, Niels, Hans, Jörg B, Tóth, Ákos, Buzgó, Lilla, Cormican, Martin, Delappe, Niall, Monaco, Monica, Giufrè, Maria, Hendrickx, Antoni PA, Samuelsen, Ørjan, Pöntinen, Anna K, Caniça, Manuela, Manageiro, Vera, Oteo-Iglesias, Jesús, Pérez-Vázquez, María, Westmo, Karin, Mäkitalo, Barbro, Palm, Daniel, Monnet, Dominique L, Kohlenberg, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2023
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176832/
https://www.ncbi.nlm.nih.gov/pubmed/37166762
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.19.2300209
Descripción
Sumario:Whole genome sequencing data of 874 Escherichia coli isolates carrying bla (NDM-5) from 13 European Union/European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and an increasing frequency of detection. Nearly a third (30.6%) of these isolates were associated with infections and more than half (58.2%) were predicted to be multidrug-resistant. Further spread of E. coli carrying bla (NDM-5) would leave limited treatment options for serious E. coli infections.

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