Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer

BACKGROUND: RNA modifications are important regulators of transcript activity and an increasingly emerging body of data suggests that the epitranscriptome and its associated enzymes are altered in human tumors. METHODS: Combining data mining and conventional experimental procedures, NSUN7 methylatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Ortiz-Barahona, Vanessa, Soler, Marta, Davalos, Veronica, García-Prieto, Carlos A., Janin, Maxime, Setien, Fernando, Fernández-Rebollo, Irene, Bech-Serra, Joan J., De La Torre, Carolina, Guil, Sonia, Villanueva, Alberto, Zhang, Pei-Hong, Yang, Li, Guarnacci, Marco, Schumann, Ulrike, Preiss, Thomas, Balaseviciute, Ugne, Montal, Robert, Llovet, Josep M., Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176850/
https://www.ncbi.nlm.nih.gov/pubmed/37173708
http://dx.doi.org/10.1186/s12943-023-01785-z

Ejemplares similares

Ejemplares similares