Cargando…
The Validation of a Precursor Lesion of Epithelial Ovarian Cancer in Fancd2-KO Mice
SIMPLE SUMMARY: The advancement of improved early detection is in part hampered by limited knowledge of ovarian cancer (OC) origin, difficulties in accessing early-stage OC in female patients and a lack of animal models to study early OC development. The Fancd2 knock-out (KO) animal model has former...
Autores principales: | Sczelecki, Sarah, Pitman, Janet L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177028/ https://www.ncbi.nlm.nih.gov/pubmed/37174061 http://dx.doi.org/10.3390/cancers15092595 |
Ejemplares similares
-
Subcellular localization of FANCD2 is associated with survival in ovarian carcinoma
por: Joshi, Sonali, et al.
Publicado: (2020) -
FANCD2 and DNA Damage
por: Nepal, Manoj, et al.
Publicado: (2017) -
The FANCD2–FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2
por: Liang, Chih-Chao, et al.
Publicado: (2016) -
Stratifying the risk of ovarian cancer incidence by histologic subtypes in the Korean Epithelial Ovarian Cancer Study (Ko‐EVE)
por: Sung, Soseul, et al.
Publicado: (2023) -
Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination
por: Liang, Zhuobin, et al.
Publicado: (2019)