Multiple and Consecutive Genome Editing Using i-GONAD and Breeding Enrichment Facilitates the Production of Genetically Modified Mice

Genetically modified (GM) mice are essential tools in biomedical research. Traditional methods for generating GM mice are expensive and require specialized personnel and equipment. The use of clustered regularly interspaced short palindromic repeats (CRISPR) coupled with improved-Genome editing via...

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Detalles Bibliográficos
Autores principales: Melo-Silva, Carolina R., Knudson, Cory J., Tang, Lingjuan, Kafle, Samita, Springer, Lauren E., Choi, Jihae, Snyder, Christopher M., Wang, Yajing, Kim, Sangwon V., Sigal, Luis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177031/
https://www.ncbi.nlm.nih.gov/pubmed/37174743
http://dx.doi.org/10.3390/cells12091343

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