Cargando…

The Activity of Natural Polymorphic Variants of Human DNA Polymerase β Having an Amino Acid Substitution in the Transferase Domain

To maintain the integrity of the genome, there is a set of enzymatic systems, one of which is base excision repair (BER), which includes sequential action of DNA glycosylases, apurinic/apyrimidinic endonucleases, DNA polymerases, and DNA ligases. Normally, BER works efficiently, but the enzymes them...

Descripción completa

Detalles Bibliográficos
Autores principales: Kladova, Olga A., Tyugashev, Timofey E., Mikushina, Elena S., Kuznetsov, Nikita A., Novopashina, Daria S., Kuznetsova, Aleksandra A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177036/
https://www.ncbi.nlm.nih.gov/pubmed/37174699
http://dx.doi.org/10.3390/cells12091300