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A User-Friendly System for Mailed Dosimetric Audits of (192)Ir or (60)Co HDR Brachytherapy Sources

SIMPLE SUMMARY: Nowadays, the options available to perform external dosimetric audits of the high dose rate (HDR) brachytherapy treatment process are limited. In this work, we present a methodology that allows for performing dosimetric audits in this field. A phantom was designed and manufactured fo...

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Autores principales: Oliver-Cañamás, Laura, Vijande, Javier, Candela-Juan, Cristian, Gimeno-Olmos, Jose, Pujades-Claumarchirant, Mª Carmen, Rovira-Escutia, Juan J., Ballester, Facundo, Perez-Calatayud, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177083/
https://www.ncbi.nlm.nih.gov/pubmed/37173950
http://dx.doi.org/10.3390/cancers15092484
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author Oliver-Cañamás, Laura
Vijande, Javier
Candela-Juan, Cristian
Gimeno-Olmos, Jose
Pujades-Claumarchirant, Mª Carmen
Rovira-Escutia, Juan J.
Ballester, Facundo
Perez-Calatayud, Jose
author_facet Oliver-Cañamás, Laura
Vijande, Javier
Candela-Juan, Cristian
Gimeno-Olmos, Jose
Pujades-Claumarchirant, Mª Carmen
Rovira-Escutia, Juan J.
Ballester, Facundo
Perez-Calatayud, Jose
author_sort Oliver-Cañamás, Laura
collection PubMed
description SIMPLE SUMMARY: Nowadays, the options available to perform external dosimetric audits of the high dose rate (HDR) brachytherapy treatment process are limited. In this work, we present a methodology that allows for performing dosimetric audits in this field. A phantom was designed and manufactured for this purpose. The criteria for its design, together with the in-house measurements for its characterization, are presented. The result is a user-friendly system that can be mailed to perform dosimetric audits in HDR brachytherapy on-site for systems using either Iridium-192 ((192)Ir) or Cobalt-60 ((60)Co) sources. ABSTRACT: Objectives: The main goal of this work is to design and characterize a user-friendly methodology to perform mailed dosimetric audits in high dose rate (HDR) brachytherapy for systems using either Iridium-192 ((192)Ir) or Cobalt-60 ((60)Co) sources. Methods: A solid phantom was designed and manufactured with four catheters and a central slot to place one dosimeter. Irradiations with an Elekta MicroSelectron V2 for (192)Ir, and with a BEBIG Multisource for (60)Co were performed for its characterization. For the dose measurements, nanoDots, a type of optically stimulated luminescent dosimeters (OSLDs), were characterized. Monte Carlo (MC) simulations were performed to evaluate the scatter conditions of the irradiation set-up and to study differences in the photon spectra of different (192)Ir sources (Microselectron V2, Flexisource, BEBIG Ir2.A85-2 and Varisource VS2000) reaching the dosimeter in the irradiation set-up. Results: MC simulations indicate that the surface material on which the phantom is supported during the irradiations does not affect the absorbed dose in the nanoDot. Generally, differences below 5% were found in the photon spectra reaching the detector when comparing the Microselectron V2, the Flexisource and the BEBIG models. However, differences up to 20% are observed between the V2 and the Varisource VS2000 models. The calibration coefficients and the uncertainty in the dose measurement were evaluated. Conclusions: The system described here is able to perform dosimetric audits in HDR brachytherapy for systems using either (192)Ir or (60)Co sources. No significant differences are observed between the photon spectra reaching the detector for the MicroSelectron V2, the Flexisource and the BEBIG (192)Ir sources. For the Varisource VS2000, a higher uncertainty is considered in the dose measurement to allow for the nanoDot response.
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spelling pubmed-101770832023-05-13 A User-Friendly System for Mailed Dosimetric Audits of (192)Ir or (60)Co HDR Brachytherapy Sources Oliver-Cañamás, Laura Vijande, Javier Candela-Juan, Cristian Gimeno-Olmos, Jose Pujades-Claumarchirant, Mª Carmen Rovira-Escutia, Juan J. Ballester, Facundo Perez-Calatayud, Jose Cancers (Basel) Article SIMPLE SUMMARY: Nowadays, the options available to perform external dosimetric audits of the high dose rate (HDR) brachytherapy treatment process are limited. In this work, we present a methodology that allows for performing dosimetric audits in this field. A phantom was designed and manufactured for this purpose. The criteria for its design, together with the in-house measurements for its characterization, are presented. The result is a user-friendly system that can be mailed to perform dosimetric audits in HDR brachytherapy on-site for systems using either Iridium-192 ((192)Ir) or Cobalt-60 ((60)Co) sources. ABSTRACT: Objectives: The main goal of this work is to design and characterize a user-friendly methodology to perform mailed dosimetric audits in high dose rate (HDR) brachytherapy for systems using either Iridium-192 ((192)Ir) or Cobalt-60 ((60)Co) sources. Methods: A solid phantom was designed and manufactured with four catheters and a central slot to place one dosimeter. Irradiations with an Elekta MicroSelectron V2 for (192)Ir, and with a BEBIG Multisource for (60)Co were performed for its characterization. For the dose measurements, nanoDots, a type of optically stimulated luminescent dosimeters (OSLDs), were characterized. Monte Carlo (MC) simulations were performed to evaluate the scatter conditions of the irradiation set-up and to study differences in the photon spectra of different (192)Ir sources (Microselectron V2, Flexisource, BEBIG Ir2.A85-2 and Varisource VS2000) reaching the dosimeter in the irradiation set-up. Results: MC simulations indicate that the surface material on which the phantom is supported during the irradiations does not affect the absorbed dose in the nanoDot. Generally, differences below 5% were found in the photon spectra reaching the detector when comparing the Microselectron V2, the Flexisource and the BEBIG models. However, differences up to 20% are observed between the V2 and the Varisource VS2000 models. The calibration coefficients and the uncertainty in the dose measurement were evaluated. Conclusions: The system described here is able to perform dosimetric audits in HDR brachytherapy for systems using either (192)Ir or (60)Co sources. No significant differences are observed between the photon spectra reaching the detector for the MicroSelectron V2, the Flexisource and the BEBIG (192)Ir sources. For the Varisource VS2000, a higher uncertainty is considered in the dose measurement to allow for the nanoDot response. MDPI 2023-04-26 /pmc/articles/PMC10177083/ /pubmed/37173950 http://dx.doi.org/10.3390/cancers15092484 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oliver-Cañamás, Laura
Vijande, Javier
Candela-Juan, Cristian
Gimeno-Olmos, Jose
Pujades-Claumarchirant, Mª Carmen
Rovira-Escutia, Juan J.
Ballester, Facundo
Perez-Calatayud, Jose
A User-Friendly System for Mailed Dosimetric Audits of (192)Ir or (60)Co HDR Brachytherapy Sources
title A User-Friendly System for Mailed Dosimetric Audits of (192)Ir or (60)Co HDR Brachytherapy Sources
title_full A User-Friendly System for Mailed Dosimetric Audits of (192)Ir or (60)Co HDR Brachytherapy Sources
title_fullStr A User-Friendly System for Mailed Dosimetric Audits of (192)Ir or (60)Co HDR Brachytherapy Sources
title_full_unstemmed A User-Friendly System for Mailed Dosimetric Audits of (192)Ir or (60)Co HDR Brachytherapy Sources
title_short A User-Friendly System for Mailed Dosimetric Audits of (192)Ir or (60)Co HDR Brachytherapy Sources
title_sort user-friendly system for mailed dosimetric audits of (192)ir or (60)co hdr brachytherapy sources
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177083/
https://www.ncbi.nlm.nih.gov/pubmed/37173950
http://dx.doi.org/10.3390/cancers15092484
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