Obesity Is Associated with Immunometabolic Changes in Adipose Tissue That May Drive Treatment Resistance in Breast Cancer: Immune-Metabolic Reprogramming and Novel Therapeutic Strategies

SIMPLE SUMMARY: Obesity is associated with metabolic changes in the immunological tumour infiltrate in breast cancer. The crosstalk between adipocytes, macrophages and proinflammatory cytokines may promote immunometabolic dysregulation and immunosuppressive phenotypes in breast tumours which may be...

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Detalles Bibliográficos
Autores principales: Savva, Constantinos, Copson, Ellen, Johnson, Peter W. M., Cutress, Ramsey I., Beers, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177091/
https://www.ncbi.nlm.nih.gov/pubmed/37173907
http://dx.doi.org/10.3390/cancers15092440

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