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LKB1 Regulates Inflammation of Fibroblast-like Synoviocytes from Patients with Rheumatoid Arthritis via AMPK-Dependent SLC7A11-NOX4-ROS Signaling

Fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA) patients have increased reactive oxygen species (ROS) levels and an impaired redox balance compared with FLS from control patients. Liver kinase B1 (LKB1) plays a key role in ROS scavenging and cellular metabolism in various cancers. He...

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Detalles Bibliográficos
Autores principales:	Lee, Ha-Reum, Yoo, Su-Jin, Kim, Jinhyun, Kang, Seong Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177119/ https://www.ncbi.nlm.nih.gov/pubmed/37174663 http://dx.doi.org/10.3390/cells12091263

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