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PRAME Is a Novel Target of Tumor-Intrinsic Gas6/Axl Activation and Promotes Cancer Cell Invasion in Hepatocellular Carcinoma

SIMPLE SUMMARY: The receptor tyrosine kinase Axl is upregulated in up to 40% of hepatocellular carcinoma (HCC) cases correlating with an unfavorable prognosis. It is an open issue how Axl and its ligand Gas6 drive disease development at a molecular level. The aim of this study was to identify target...

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Detalles Bibliográficos
Autores principales:	Hedrich, Viola, Breitenecker, Kristina, Ortmayr, Gregor, Pupp, Franziska, Huber, Heidemarie, Chen, Doris, Sahoo, Sarthak, Jolly, Mohit Kumar, Mikulits, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177160/ https://www.ncbi.nlm.nih.gov/pubmed/37173882 http://dx.doi.org/10.3390/cancers15092415

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