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Use of the Dialkylcarbamoylchloride Dressing in the Care of Central Venous Access Exit Site in a Pediatric and Neonatal Population

Dialkylcarbamoylchloride dressing is a fatty acid derivative that has been shown in vitro to bind a number of pathogenic microorganisms. The purpose of this prospective study was to evaluate the safety and the efficacy of this technology in the care of the exit site of central venous catheter in a p...

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Autores principales: Lamberti, Giorgio, Domenichelli, Vincenzo, Straziuso, Simona, Pelusi, Gabriella, Natile, Miria, Ancora, Gina, Barone, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177172/
https://www.ncbi.nlm.nih.gov/pubmed/37174912
http://dx.doi.org/10.3390/diagnostics13091520
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author Lamberti, Giorgio
Domenichelli, Vincenzo
Straziuso, Simona
Pelusi, Gabriella
Natile, Miria
Ancora, Gina
Barone, Giovanni
author_facet Lamberti, Giorgio
Domenichelli, Vincenzo
Straziuso, Simona
Pelusi, Gabriella
Natile, Miria
Ancora, Gina
Barone, Giovanni
author_sort Lamberti, Giorgio
collection PubMed
description Dialkylcarbamoylchloride dressing is a fatty acid derivative that has been shown in vitro to bind a number of pathogenic microorganisms. The purpose of this prospective study was to evaluate the safety and the efficacy of this technology in the care of the exit site of central venous catheter in a paediatric and neonatal population. Methods: The study was conducted from September 2020 to December 2022 at the Infermi Hospital in Rimini. Central venous catheters were placed using the SIC bundle for insertion. Dialkylcarbamoylchloride dressing was placed below the subcutaneous anchoring at the time of CVC placement and at each dressing change. Data about the catheters and the exit site were recorded and then compared with an historical cohort. Results: 118 catheters were placed during the studied period. The dialkylcarbamoylchloride dressing was well-tolerated. No case of systemic or local infection was recorded. The comparison with the historical cohort showed a reduction in the rate of exit site infection (p value 0.03). Conclusion: Dialkylcarbamoylchloride dressing is well-tolerated in paediatric and neonatal population. It represents a promising tool as a strategy for infection prevention.
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spelling pubmed-101771722023-05-13 Use of the Dialkylcarbamoylchloride Dressing in the Care of Central Venous Access Exit Site in a Pediatric and Neonatal Population Lamberti, Giorgio Domenichelli, Vincenzo Straziuso, Simona Pelusi, Gabriella Natile, Miria Ancora, Gina Barone, Giovanni Diagnostics (Basel) Article Dialkylcarbamoylchloride dressing is a fatty acid derivative that has been shown in vitro to bind a number of pathogenic microorganisms. The purpose of this prospective study was to evaluate the safety and the efficacy of this technology in the care of the exit site of central venous catheter in a paediatric and neonatal population. Methods: The study was conducted from September 2020 to December 2022 at the Infermi Hospital in Rimini. Central venous catheters were placed using the SIC bundle for insertion. Dialkylcarbamoylchloride dressing was placed below the subcutaneous anchoring at the time of CVC placement and at each dressing change. Data about the catheters and the exit site were recorded and then compared with an historical cohort. Results: 118 catheters were placed during the studied period. The dialkylcarbamoylchloride dressing was well-tolerated. No case of systemic or local infection was recorded. The comparison with the historical cohort showed a reduction in the rate of exit site infection (p value 0.03). Conclusion: Dialkylcarbamoylchloride dressing is well-tolerated in paediatric and neonatal population. It represents a promising tool as a strategy for infection prevention. MDPI 2023-04-23 /pmc/articles/PMC10177172/ /pubmed/37174912 http://dx.doi.org/10.3390/diagnostics13091520 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lamberti, Giorgio
Domenichelli, Vincenzo
Straziuso, Simona
Pelusi, Gabriella
Natile, Miria
Ancora, Gina
Barone, Giovanni
Use of the Dialkylcarbamoylchloride Dressing in the Care of Central Venous Access Exit Site in a Pediatric and Neonatal Population
title Use of the Dialkylcarbamoylchloride Dressing in the Care of Central Venous Access Exit Site in a Pediatric and Neonatal Population
title_full Use of the Dialkylcarbamoylchloride Dressing in the Care of Central Venous Access Exit Site in a Pediatric and Neonatal Population
title_fullStr Use of the Dialkylcarbamoylchloride Dressing in the Care of Central Venous Access Exit Site in a Pediatric and Neonatal Population
title_full_unstemmed Use of the Dialkylcarbamoylchloride Dressing in the Care of Central Venous Access Exit Site in a Pediatric and Neonatal Population
title_short Use of the Dialkylcarbamoylchloride Dressing in the Care of Central Venous Access Exit Site in a Pediatric and Neonatal Population
title_sort use of the dialkylcarbamoylchloride dressing in the care of central venous access exit site in a pediatric and neonatal population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177172/
https://www.ncbi.nlm.nih.gov/pubmed/37174912
http://dx.doi.org/10.3390/diagnostics13091520
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