Senolytic Flavonoids Enhance Type-I and Type-II Cell Death in Human Radioresistant Colon Cancer Cells through AMPK/MAPK Pathway

SIMPLE SUMMARY: The role of autophagy and senescence in cancer resistance to ionizing radiation as a response to genotoxic stress is still only partially explored. The flavonoids quercetin and fisetin have previously been shown to sensitize cancer cells resistant to radiotherapy by targeting p16(INK...

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Detalles Bibliográficos
Autores principales: Russo, Maria, Moccia, Stefania, Luongo, Diomira, Russo, Gian Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177236/
https://www.ncbi.nlm.nih.gov/pubmed/37174126
http://dx.doi.org/10.3390/cancers15092660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177236/
https://www.ncbi.nlm.nih.gov/pubmed/37174126
http://dx.doi.org/10.3390/cancers15092660

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