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Senolytic Flavonoids Enhance Type-I and Type-II Cell Death in Human Radioresistant Colon Cancer Cells through AMPK/MAPK Pathway
SIMPLE SUMMARY: The role of autophagy and senescence in cancer resistance to ionizing radiation as a response to genotoxic stress is still only partially explored. The flavonoids quercetin and fisetin have previously been shown to sensitize cancer cells resistant to radiotherapy by targeting p16(INK...
Autores principales: | Russo, Maria, Moccia, Stefania, Luongo, Diomira, Russo, Gian Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177236/ https://www.ncbi.nlm.nih.gov/pubmed/37174126 http://dx.doi.org/10.3390/cancers15092660 |
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