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Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future
Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory failure that accounts for 10% of admissions to the ICU and is associated with approximately 40% mortality in severe cases. Despite significant mortality and healthcare burden, the mainstay of management remains s...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177247/ https://www.ncbi.nlm.nih.gov/pubmed/37174920 http://dx.doi.org/10.3390/diagnostics13091528 |
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author | Ramji, Husayn F. Hafiz, Maida Altaq, Hiba Hammad Hussain, Syed Talal Chaudry, Fawad |
author_facet | Ramji, Husayn F. Hafiz, Maida Altaq, Hiba Hammad Hussain, Syed Talal Chaudry, Fawad |
author_sort | Ramji, Husayn F. |
collection | PubMed |
description | Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory failure that accounts for 10% of admissions to the ICU and is associated with approximately 40% mortality in severe cases. Despite significant mortality and healthcare burden, the mainstay of management remains supportive care. The recent pandemic of SARS-CoV-2 has re-ignited a worldwide interest in exploring the pathophysiology of ARDS, looking for innovative ideas to treat this disease. Recently, many trials have been published utilizing different pharmacotherapy targets; however, the long-term benefits of these agents remain unknown. Metabolomics profiling and stem cell transplantation offer strong enthusiasm and may completely change the outlook of ARDS management in the near future. |
format | Online Article Text |
id | pubmed-10177247 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101772472023-05-13 Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future Ramji, Husayn F. Hafiz, Maida Altaq, Hiba Hammad Hussain, Syed Talal Chaudry, Fawad Diagnostics (Basel) Review Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory failure that accounts for 10% of admissions to the ICU and is associated with approximately 40% mortality in severe cases. Despite significant mortality and healthcare burden, the mainstay of management remains supportive care. The recent pandemic of SARS-CoV-2 has re-ignited a worldwide interest in exploring the pathophysiology of ARDS, looking for innovative ideas to treat this disease. Recently, many trials have been published utilizing different pharmacotherapy targets; however, the long-term benefits of these agents remain unknown. Metabolomics profiling and stem cell transplantation offer strong enthusiasm and may completely change the outlook of ARDS management in the near future. MDPI 2023-04-24 /pmc/articles/PMC10177247/ /pubmed/37174920 http://dx.doi.org/10.3390/diagnostics13091528 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Ramji, Husayn F. Hafiz, Maida Altaq, Hiba Hammad Hussain, Syed Talal Chaudry, Fawad Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future |
title | Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future |
title_full | Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future |
title_fullStr | Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future |
title_full_unstemmed | Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future |
title_short | Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future |
title_sort | acute respiratory distress syndrome; a review of recent updates and a glance into the future |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177247/ https://www.ncbi.nlm.nih.gov/pubmed/37174920 http://dx.doi.org/10.3390/diagnostics13091528 |
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