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Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future

Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory failure that accounts for 10% of admissions to the ICU and is associated with approximately 40% mortality in severe cases. Despite significant mortality and healthcare burden, the mainstay of management remains s...

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Autores principales: Ramji, Husayn F., Hafiz, Maida, Altaq, Hiba Hammad, Hussain, Syed Talal, Chaudry, Fawad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177247/
https://www.ncbi.nlm.nih.gov/pubmed/37174920
http://dx.doi.org/10.3390/diagnostics13091528
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author Ramji, Husayn F.
Hafiz, Maida
Altaq, Hiba Hammad
Hussain, Syed Talal
Chaudry, Fawad
author_facet Ramji, Husayn F.
Hafiz, Maida
Altaq, Hiba Hammad
Hussain, Syed Talal
Chaudry, Fawad
author_sort Ramji, Husayn F.
collection PubMed
description Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory failure that accounts for 10% of admissions to the ICU and is associated with approximately 40% mortality in severe cases. Despite significant mortality and healthcare burden, the mainstay of management remains supportive care. The recent pandemic of SARS-CoV-2 has re-ignited a worldwide interest in exploring the pathophysiology of ARDS, looking for innovative ideas to treat this disease. Recently, many trials have been published utilizing different pharmacotherapy targets; however, the long-term benefits of these agents remain unknown. Metabolomics profiling and stem cell transplantation offer strong enthusiasm and may completely change the outlook of ARDS management in the near future.
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spelling pubmed-101772472023-05-13 Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future Ramji, Husayn F. Hafiz, Maida Altaq, Hiba Hammad Hussain, Syed Talal Chaudry, Fawad Diagnostics (Basel) Review Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory failure that accounts for 10% of admissions to the ICU and is associated with approximately 40% mortality in severe cases. Despite significant mortality and healthcare burden, the mainstay of management remains supportive care. The recent pandemic of SARS-CoV-2 has re-ignited a worldwide interest in exploring the pathophysiology of ARDS, looking for innovative ideas to treat this disease. Recently, many trials have been published utilizing different pharmacotherapy targets; however, the long-term benefits of these agents remain unknown. Metabolomics profiling and stem cell transplantation offer strong enthusiasm and may completely change the outlook of ARDS management in the near future. MDPI 2023-04-24 /pmc/articles/PMC10177247/ /pubmed/37174920 http://dx.doi.org/10.3390/diagnostics13091528 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ramji, Husayn F.
Hafiz, Maida
Altaq, Hiba Hammad
Hussain, Syed Talal
Chaudry, Fawad
Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future
title Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future
title_full Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future
title_fullStr Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future
title_full_unstemmed Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future
title_short Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future
title_sort acute respiratory distress syndrome; a review of recent updates and a glance into the future
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177247/
https://www.ncbi.nlm.nih.gov/pubmed/37174920
http://dx.doi.org/10.3390/diagnostics13091528
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