Molecular Chaperones’ Potential against Defective Proteostasis of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a neuronal degenerative condition identified via a build-up of mutant aberrantly folded proteins. The native folding of polypeptides is mediated by molecular chaperones, preventing their pathogenic aggregation. The mutant protein expression in ALS is linked wit...

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Detalles Bibliográficos
Autores principales: Kinger, Sumit, Dubey, Ankur Rakesh, Kumar, Prashant, Jagtap, Yuvraj Anandrao, Choudhary, Akash, Kumar, Amit, Prajapati, Vijay Kumar, Dhiman, Rohan, Mishra, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177248/
https://www.ncbi.nlm.nih.gov/pubmed/37174703
http://dx.doi.org/10.3390/cells12091302

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